%0 Journal Article 
%T The ovarian cancers in geriatric population: the validity of inflammatory markers, malignancy risk indices 1, 2, 3, 4, and CA-125 levels in malignancy discrimination of adnexal masses
%A F. Vural
%A N. Aka
%A S. Ertaş
%A G. Köse
%A E.C. Tüfekçi
%D 2016
%J European Journal of Gynaecological Oncology
%R 10.12892/ejgo3271.2016
%P 846-851
%V 37
%N 6
%U {https://www.ejgo.net/articles/10.12892/ejgo3271.2016}
%8 2016-12-10
%X <p><i>Purpose: </i>To investigate the predictive value of the Risk of Malignancy Index (RMI), CA-125, and inflammatory markers in discriminating ovarian cancers (OCs). <i>Materials and Methods: </i>The postmenopausal (PM) women (n = 139) with adnexal masses who underwent surgery were included. The predictive value of CA-125, RMI (1, 2, 3, and 4) and inflammatory markers [neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR)] were calculated in geriatric (G) and non-geriatric women. <i>Results: </i>OCs had significantly increased NLR and PLR. RMI models were highly reliable in PM (Kappa: 0.642-0.715; AUC: 0.907-0.934). CA-125 measurement alone had good accuracy and moderate reliability in PM (kappa: 0.507-0.587), excellent accuracy and moderate reliability in G, NLR, and PLR predicting OCs, showed fair agreement in the PM, while PLR had a moderate agreement with G. <i>Conclusion: </i>RMI algorithms were the best models for malignancy prediction. However, the rise of PLR and CA-125 levels in a G population may be used as referring adnexal masses to gynecologic oncologists.</p><p><br></p>