RT  - European Journal of Gynaecological Oncology
ID  - 10.12892/ejgo200706516
T1  - Ovarian gonodoblastoma with yolk sac tumor in a young 46, XX female: case report
A1  - E. E rdemoglu
A1  - S. Ozen
K1  - Gonodoblastoma; Endodermal sinus tumor; Yolk sac tumor; Immunohistochemistry; Tumor markers
YR  - 2007
SP  - 516
AB  - <p><i>Background: </i>Gonodoblastomas with ovarian germ cell tumors
(OGCTs) other than dysgerminoma are very unusual. This is the first case report
of a pure endodermal sinus tumor of the ovary with gonodoblastoma in a 46 XX,
female. <i>Case: </i>A 19-year-old female was admitted to our hospital with
an abdominal mass and pain. She had elevated levels of CA-125 and AFP.
Fertility sparing surgery was undertaken and revealed a Stage IA endodermal
sinus tumor and gonodoblastoma in the same ovary. The patient refused chemotherapy
and was followed-up for six months without disease. Conclusion: Gonodoblastomas may occur in conjunction with
OGCTs. Tumor markers and immunohistochemical examination may help in the
diagnosis of these OGCTs with gonodoblastoma.</p>