RT  - European Journal of Gynaecological Oncology
ID  - 10.12892/ejgo201103269
T1  - Safety and efficacy of a splenectomy during debulking surgery for Müllerian carcinoma
A1  - Uehara
A1  - T. Onda
A1  - S. Togami
A1  - T. Amano
A1  - M. Tanikawa
A1  - M. Sawada
A1  - S. Ikeda
A1  - T. Kato
A1  - T. Kasamatsu
K1  - Debulking surgery; Müllerian carcinoma; Prognosis; Spleen metastasis; Splenectomy
YR  - 2011
SP  - 269
AB  - <p><i>Purpose: </i>This study was designed to assess the safety and efficacy of a splenectomy and to analyze the prognostic factors of Müllerian carcinoma with spleen metastasis. <i>Methods:</i> We reviewed the medical records of 11 patients with Müllerian carcinoma who underwent a splenectomy between 1997 and 2007. The treatment outcome of these patients was examined and the possible prognostic factors were investigated by univariate analysis. <i>Results: </i>Four and seven patients underwent a splenectomy for primary and recurrent disease, respectively. A complete resection was achieved in eight patients. A bloodtransfusion was not required and only two mild postoperative complications were observed. The median and five-year survivals of all patients following treatment were 39 months and 39%, respectively. Older patients ( 60 years old) and patients with a poor performance status (PS2) had a poorer prognosis by univariate analysis. <i>Conclusions:</i> A splenectomy can be performed safely and effectively during debulking surgery for appropriately selected patients with primary or recurrent Müllerian carcinoma. </p>