RT  - European Journal of Gynaecological Oncology
ID  - 10.12892/ejgo2810.2016
T1  - Malignant mesonephric tumor of the cervix with an initial manifestation as pulmonary metastasis: case report and review of the literature
A1  - M.K. Yeo
A1  - S.Y. Choi
A1  - M. Kim
A1  - K.H. Kim
A1  - K.S. Suh
K1  - Malignant mesonepehric tumor; Mesonephric adenocarcinoma; Uterus; Cytology; Pathology; Immunohistochemistry.
YR  - 2016
SP  - 270
AB  - <p>Malignant mesonephric tumor (MMT) is a relatively uncommon malignancy of the female genital tract. The diagnosis of metastatic MMT is difficult because cytological, pathological, immunohistochemical characteristics of MMT are under-recognized. The authors present a 55-year-old female with metastatic pulmonary nodules. The bronchial washing cytology revealed three dimensional clusters of bland epithelial cells with slight nuclear grooves. A corresponding lung histology had ductal or tubular clusters of epithelial cells with intraglandular eosinophilic materials. These epithelial cells were positive for immunohistochemical stain of CD10, suggesting metastasis from MMT. The cervical smear showed clusters of bland, gland-forming epithelial cells with intraglandular eosinophilic materials. On histologic examination, mesonephric adenocarcinoma with papillary and solid proliferation was identified in the uterine cervix. A review of the literature for 72 cases of MMT is also included. Clinical and cytopathological features of MMT are herein made available.</p>