RT  - European Journal of Gynaecological Oncology
ID  - 10.12892/ejgo3026.2016
T1  - Study of clinical diagnosis of cervical glandular intraepithelial neoplasia
A1  - S. Yang
A1  - W. Duan
A1  - W. Kong
A1  - L. Zhu
A1  - Y. Wu
K1  - Cervical glandular intraepithelial neoplasia; Endocervical glandular dysplsia; Diagnosis.
YR  - 2016
SP  - 539
AB  - <p><i>Objective: </i>To preliminarily evaluate the clinical significance of different methods in diagnosis of cervical glandular intraepithelial neoplasia (CGIN). <i>Materials and Methods: </i>Clinical manifestations, ThinPrep cytologic test (TCT), cervical biopsy, and pathological features of 106 patients with CGIN admitted to Beijing Obstetrics and Gynecology Hospital between 2008 and 2011 were retrospectively analyzed. <i>Results: </i>Among 146 cases diagnosed with CGIN, 87 (59.6%) had L-CGIN and 59 (40.4%) H-CGIN. Thirty-seven patients (25.6%) were found to have simple CGIN and 109 (74.6%) had CGIN complicated with cervical intraepithelial neoplasia (CIN). TCT revealed atypical glandular cells (AGC) in 20 patients (13.7%), six of whom had L-CGIN (6.9%) and 14 (23.7%) had H-CGIN with statistical significance between two groups (<i>p </i>&lt; 0.05). TCT detected AGC in 13 cases (35.1%) with simple CGIN and seven with mixed CGIN (6.4%) (<i>P&lt;</i>0.05). Endocervical curettage (ECC) revealed AGC abnormality in ten cases (25.6%). Cervical biopsy under colposcope revealed 32 patients (22.9%) had CGIN, including 15 L-CGIN (18.3%), and 17 H-CGIN (29.3%) with no statistical significance (<i>p &gt; </i>0.05). Among those diagnosed with CGIN by colposcope-assisted cervical biopsy, 19 (51.4%) had simple CGIN and 13 (11.9%) mixed CGIN (<i>p &lt; </i>0.05). <i>Conclusion: </i>Preoperative diagnostic rate of simple CGIN was higher than CGIN complicated with CIN</p>