RT - European Journal of Gynaecological Oncology ID - 10.12892/ejgo3050.2016 T1 - A case of ovarian small cell carcinoma of the pulmonary type that was observed as it developed A1 - R. Kumasaka A1 - Y. Yokoyama A1 - K. Fuchinoue A1 - H. Mizunuma A1 - R. Taniguchi A1 - T. Hashimoto A1 - T. Oda A1 - T. Kusumi K1 - Ovarian small cell carcinoma; Pulmonary type; Type 1 ovarian malignancy; CD56; Synaptophysin; Irinotecan and cisplatin. YR - 2016 SP - 710 AB -

In the case reported here, the authors observed ovarian small cell carcinoma of the pulmonary type as it developed. The patient was a 48-year-old woman who underwent a hysterectomy for CIN3 in 2007. A year later, the woman underwent screening for ovarian cancer. A gradually growing ovarian mass was noted. This mass was found to be a mixed tumor. This mixed tumor grew to 36 mm in size, and six months later it had enlarged to 119 mm. After surgery, the tumor was pathologically diagnosed as an ovarian small cell carcinoma of the pulmonary type with a neuroendocrine nature that was positive for CD56 and synaptophysin. Postoperatively, the patient received six courses of combined therapy with irinotecan and cisplatin (CPT-P therapy), and the patient has survived diseasefree for over two years. Findings suggested that ovarian small cell carcinoma of the pulmonary type is a type 1 ovarian malignancy that develops through an adenoma-carcinoma sequence.