RT - European Journal of Gynaecological Oncology ID - 10.12892/ejgo3550.2017 T1 - Management of cervical dysplasia in patient with Müllerian anomaly: diagnostic and therapeutic challenges A1 - R. Sparic A1 - J. Dotlic A1 - J. Kovac A1 - I. Babovic A1 - S. Buzadzic A1 - L. Mirkovi A1 - L. Nejkovic A1 - J. Stamenkovic K1 - Uterus duplex; Cervical dysplasia; Conization; Hysterectomy; Diagnosis; Therapy. YR - 2017 SP - 469 AB -

Purpose: The study aim was to report diagnostic and therapeutic challenges in treatment of a patient with cervical dysplasia and congenital uterine anomaly. Case Report: A 53-year-old women with Mullerian anomaly – uterus duplex (bicorporal septate uterus) and Yshaped endocervical canal was referred due to repeated abnormal Pap smears. She underwent endocervical curettage of both canals and the endocervical septum biopsy which revealed presence of cervical intraepithelial neoplasia (CIN) III. Cervical conization was considered technically unfeasible because of abnormal cervical anatomy (lesions deep in the cervical canal on the cervical bifurcation where the cervical wall is the thickest). Classical open abdominal hysterectomy was performed. Patient had two almost equally-sized, symmetrical uterine bodies connected in the isthmico-cervical region, with normal left and obstructed right hemi-vagina. Postoperative histopathological findings confirmed that dysplasia was located in the region where two endocervical canals conjoined. Conclusion: Diagnostic and therapeutic approach to patients with uterine anomalies has to be individualized, based on anomaly type, patient's age, reproductive history, and patient's preferences.