RT - European Journal of Gynaecological Oncology ID - 10.12892/ejgo3554.2017 T1 - Chemotherapy-induced differentiation to cure botryoid rhabdomyosarcoma: a case report and review of the literature A1 - T. Assi A1 - E. El Rassy A1 - G. Abi-Tayeh A1 - C. Sader-Ghorra A1 - G. Abadjian A1 - R. Eid A1 - T. Moussa A1 - F. Farhat A1 - J. Kattan K1 - Chemotherapy; Botryoid rhabdomyosarcoma; Cervix; Cytodifferentiation. YR - 2017 SP - 323 AB -

Rhabdomyosarcoma (RMS) occurs rarely in adults and constitutes 2-6% of all uterine neoplasms. The authors report the case of a 26-year-old woman diagnosed with botryoid RMS that presented discordant progression results on follow up imaging and cytodifferentiation on pathologic control. This case showed that radiological evaluation could be misleading as the tumor demonstrated chemotherapy-induced differentiation without volume reduction. This case illustrates the limitations of using the imaging anatomical dimensions of sarcomas for treatment planning and highlights the potential role of functional imaging to assess the response to treatment.