RT - European Journal of Gynaecological Oncology ID - 10.12892/ejgo4767.2019 T1 - Clear cell carcinoma arising from abdominal wall endometriosis with lymph node metastasis – a rare case report and review of the literature A1 - S. Kim A1 - K. J. Min A1 - S. Lee A1 - J. H. Hong A1 - J. K. Lee A1 - N. W. Lee A1 - J. Y. Song K1 - Clear cell carcinoma; Endometriosis; Lymph node; Metastasis. YR - 2019 SP - 1047 AB -
Abdominal wall endometriosis represents 1-2% of all endometriotic lesions. The malignant transformation of abdominal wall en-dometriosis is rare, though it can occur. Herein the authors report a rare case of clear cell adenocarcinoma arising from abdominal wall endometriosis with extensive lymph node metastasis. In this case, a 51-year-old woman presented with a growing mass in the right periumbilical area. Computed tomography scan revealed a 5-cm solid mass located on the right rectus muscle. A punch biopsy of the abdominal lesion was performed and histology showed metastatic adenocarcinoma of unknown origin. She had a surgical history of la-paroscopic subtotal hysterectomy with right salpingo-oophorectomy. The patient underwent radical excision of the mass, trachelectomy, left salpingo-oophorectomy, and lymph node dissection. The abdominal wall mass showed clear cell adenocarcinoma arising from en-dometriosis on histology. There were extensive lymph node metastases. The patient underwent adjuvant chemotherapy. Both lymphatic and local invasion are key routes of clear cell adenocarcinoma arising from abdominal wall endometriosis. Extensive lymph node metas-tasis could be associated with poor prognosis.