Bilateral primary squamous cell carcinoma of the ovary: A case report of isolated metastasis to the lateral pelvic wall

Primary squamous cell carcinoma of the ovary is rare. The majority of cases arise most commonly from the lining of a dermoid cyst, and less often in endometriosis or a Brenner tumor. A 40-year-old woman underwent exploratory laparotomy and was found to have a right ovarian tumor adherent to the lateral pelvic wall with no ascites. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, pelvic lymphadenectomy, infracolic omentectomy, appendectomy, and right nephrectomy for bilateral primary squamous cell carcinoma of the ovary. She was started on multiagent chemotherapy. On follow-up after two years the patient had died of cerebral metastases. To our knowledge in this report we present the first case in the English literature of bilateral pure squamous cell carcinoma of the ovary.

Squamous cell carcinoma; Ovary

[1] Scully R. E., Young R.H., Clement P. B.: "Transitional and squarnous cell tumors". In: "Turnors of the ovary, maldeveloped gonads, fallopian tube, and broad ligament. Atlas of Turnor Pathology", Third series, fascicle 23, Rosai J., Sobin L. H. (Eds.), Washington D. C., 1988, 153.

[2] Young R.H., Clernent P. B., Scully R. E.: "The ovary". In: "Diagnostic Surgical P athology". Sternberg S. S. (Ed.) Third edition, Lippincott, Williarns and Wilkins, P hiladelphia, 1999, 2307.

[3] Pins M. R., Young R.H., Daly W. J., Scully R. E.: "Primary squamous cell carcinorna of the ovary. A report of 37 cases". Arn. J Surg. Pathol., 1996, 20, 823.

[4] Wauters C. C., Srnedts F., Gerrits L. G., Bosman F. T., Ramaekers F. C.: "Keratins 7 and 20 as diagnostic markers of carcinornas to the ovary". Hum. Pathol., 1995, 26, 852.

[5] Kikkawa F., Ishikawa H., Tamakoshi K., Nawa A., Suganuma N., Tornoda Y.: "Squamous cell carcinoma arising from rnature cystic teratoma of the ovary: A clinicopathologic analysis". Obstet Gynecol., 1997, 89, 1017.

[6] Eltabbakh G. H., Hempling R. E., Recio F. 0., O'Neill C. P: "Remarkable response of primary squamous cell carcinoma of the ovary to paclitaxel and cisplatin". Obstet. Gynecol., 1998, 91, 844.

[7] Ohtani K., Sakamoto H., Masaoka N., Shimada K., Kanaeda T., Kurihara M. et al.: "A case of rapidly growing ovarian squamous cell carcinoma successfully controlled by weekly paclitaxel-carboplatin administration". Gynecol. Oncol., 2000, 79, 55.