Article Data

  • Views 1104
  • Dowloads 115

Original Research

Open Access

Current vulvar cancer treatment in Bulgaria

  • S. Ivanov1,*,

1National Specialized Hospital for Active Treatment in Oncology, Gynecologic-Oncology Clinic, Sofia, Bulgaria

DOI: 10.12892/ejgo200202161 Vol.23,Issue 2,March 2002 pp.161-162

Published: 10 March 2002

*Corresponding Author(s): S. Ivanov E-mail:

Abstract

Purpose of investigation: Our aim was to outline the treatment of carcinoma of the vulva at the National Oncological Centre in Sofia, Bulgaria.

Methods: We examined the records of 250 patients over a 10-year period treated at the Gynaecologic-Oncology Clinic of our Centre.

Results: There were 130 patients (52%) treated with surgery and radiation. There were 120 patients (48%) treated by surgery only. Thirty of these patients were treated by pelvic exenteration with radical vulvectomy. The five-year survival rate was 36% - 12 patients. The 1-year survival rate for all patients was 80% - 200 patients. The five-year survival rate was 50%.

Discussion: We have results similar to other clinics in the world working in this field. We now emphasize external radiation for advanced disease but the treatment must be individualized.

Conclusion: We have outlined the treatment of carcinoma of the vulva at our Centre, over a 10-year period.

Keywords

Vulvar cancer; Surgery; Radiotherapy


Cite and Share

S. Ivanov. Current vulvar cancer treatment in Bulgaria. European Journal of Gynaecological Oncology. 2002. 23(2);161-162.

References

[1] Hacker N. F., van der Velden J.: "Conservative management of early vulvar cancer". Cancer, 1993, 71 (5), 1673.

[2] Origini M., Sideri M., Garsia S. et al.: "Prognostic value of pathological patterns of lymph node positivity in squamous cell carcinoma of the vulva Stage III and IVA FIGO". Gynecol. Oncol., 1992, 45, 313.

[3] Boronow R. C.,H ickman T. B.,R eagan M. T. et al.: "Combined therapy as an alternative to exenteration for locally advanced vulvaginal cancer". Am. J. Clin. Oncol., 1987,10, 171.

[4] Luqi G.,R aspagliesi F.,Z ucali R. et al.: "Combined preoperative chemoradiation followed by radical surgery in locally advanced vulvar cancer". Cancer, 1996, 77, 1472.

[5] Onnis A.,Marchetti M.,S ilvestri P.: "Surgical strategies in vulvar cancer". Eur. J. Gynecol., 1994, 15 (3), 173.

[6] Onnis A., Marchetti M., Maggino T., De Toffoli J.: "Clinical experience in gynecological cancer management - Vulvar cancer". Ew: J. Gynaecol. Oneal., 1990, 1l (3), 161.

[7] Onnis A., Marchetti M., Maggi no T.: "Carcinoma of the vulva: critical analysis of survival and treatment of recurrences". Clin. Exp Obst. Gyn., 1992, 19 (2), 87.

[8] Onnis A., Marchetti M., Maggino T.: "Radical non mutilant surgery in vulvar cancer". Proceedings of International Meeting of Gynaecological Oncology. Venice-Lido (Italy) April 21s',SOG(ed.) Italy, 1985, 159.

[9] Onnis A.: "New techniques and prospectives for invasive carcinoma of the vulva". Ew: J. Gynaecol. Oneal., 1987, 18 (4-5), 308.

[10] Marchetti M., Onnis A.: "Prognostic value of protein p53 and Ki67 in invasive vulvar squamous cell carcinoma". II. Congress of Slovene Gynecologists and Obstetricians with International participation, 19-23 November 2000, Portoroz, Slovenia.

Abstracted / indexed in

Web of Science (WOS) (On Hold)

Journal Citation Reports/Science Edition

Google Scholar

JournalSeek

Submission Turnaround Time

Top