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Case Reports

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Melanocytic dysplasia and multiple melanoma of the vulva

  • G. Fabrizi1
  • G. F. Zannoni2
  • L. I. Lopez3
  • G. Massi2,*,

1Department of Dermatology, Italy

2Pathology,Catholic University Medical School, Rome, Italy

3Department of Gynaecology, Columbus Medical Centre, Rome, Italy

DOI: 10.12892/ejgo200204323 Vol.23,Issue 4,July 2002 pp.323-324

Published: 10 July 2002

*Corresponding Author(s): G. Massi E-mail:

Abstract

We report a case of a 24-year-old woman with multiple pigmented lesions on her vulva. Histologically the lesions showed a heterogeneous pattern: the majority consisted of melanoma in situ and invasive melanoma; in a few lesions a much less clear-cut picture was found with only melanocytic dysplasia of various degrees. Our case shows the relationship between anomalous melanocytic proliferation of the vulva and vulvar melanoma and underlines the necessity of a thorough check of all melanocytic vulvar lesions also in young patients.

Keywords

Vulvar multiple melanoma; Vulvar melanocytic dysplasia; Melanoma precursors

Cite and Share

G. Fabrizi,G. F. Zannoni,L. I. Lopez,G. Massi. Melanocytic dysplasia and multiple melanoma of the vulva. European Journal of Gynaecological Oncology. 2002. 23(4);323-324.

References

[1] Bradgate M.G.,R ollason T. P.,M cconkey C. C. et al.: "Malignant melanoma of vulva: a clinico-pathological study of 50 women" Br. J. Obst et. Gynaecol., 1990, 97, 124.

[2] Tasseron E. W. K., Van der Esch E. P., Hart A. A. M. et al.: "A Chnicopathological Study of 30 melanomas of the vulva". Gynecol Oncol., 1992, 42, 170.

[3] Podczaski E.,A rthur A. B. D.,K aminsky P. et al.: "A patient with multiple malignant melanoma of the lower genital tract". Gynecol Oneal., 1990, 37, 422.

[4] Kerley S. W., Blute L. M., Keeney L. G.: "Multifocal malignant melanoma arising in vesicovaginal melanosis". Arch. Pathol. Lab Med., 1991, 115, 950.

[5] Ohashi K., Kasuga T., Tanaka N. et al.: "Malignant melanoma of the oral cavity: Heterogeneity of pathological and clinical features". Virchows Archiv. a Pathol. Anat., 1992, 420, 43.

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