Malignant rhabdoid tumor of the clitoris in an elderly patient: report of a case

Malignant rhabdoid tumors of the vulva are rare neoplasms which most of the time show aggressive behavior and a dismal prognosis. We report a case of malignant rhabdoid tumor of the clitoris occurring in an elderly patient. Due to the similarities that these neoplasms show with other low-differentiated tumors, immunohistochemical and ultrastructural assessment should always be conducted so that accurate diagnosis is achieved. Individualized extensive surgical treatment might decrease relapsing disease.

Malignant rhabdoid tumor; Vulva; Immunohistochemistry; Clinical management

[1] Brand A., Covert A.: "Malignant rhabdoid tumor of the vulva: case report and review of the literature with emphasis on clinical management and outcome". Gynecol. Oneal., 2001, 80, 99.

[2] Hall D., Grimes M., Goplerud D.: "Case report: epithelioid sarcoma of the vulva". Gynecol. Oneal., 1980, 9, 237.

[3] Kodet R., Newton W., Sachs N. et al.: "Rhabdoid tumors of soft tissues: a clinicopathological study of 26 cases enrolled on the Intergroup Rhabdomyosarcoma Study". Hum. Pathol., 1991, 22, 674.

[4] Rodolakis A., Diakomanolis E., Voulgaris Z. et al.: "Squamous Vulvar Cancer: a clinically based individualization of treatment". Gynecol. Oneal., 2000, 78, 346.

[5] Cho K. R., Rosenshein N. B., Epstein J. I.: "Malignant rhabdoid tumor of the uterus". Int. J. Gynecol. Pathol., 1989, 8, 381.

[6] Tsuda H., Maed K., Hashiguchi Y. et al.: "Malignant rhabdoid tumor of the uterine cervix". BJOG, 200 I, 108 (I), 120.

[7] Enziger F. M., Weiss S. W.: "Immunohistochemistry of soft tissue lesions". In: Enziger F. M., Weiss S. W. eds. "Soft tissue tumors" Third edition. St Louis: C. V. Mosby, 1995, 139.

[8] Wilkinson E. J.: "Premalignant and malignant tumors of the vulva". In: Kurman R. J. ed. Blaustein's Pathology of the female Genital Tract. New York: Springer-Verlag 1994, 87.

[9] Guillou L., Wadden C., Coindre J. M. et al.: "«Proximal-type» epithehoid_ sarcoma, a dinstinctive aggressive neoplasm showing rhabdoid features: clinicopathologic, immunohistochemical and ultrastructural study of a series". Am. J. Surg. Pathol., 1997, 21, 130.

[10] Hinze P., Feyler S., Berndt J. et al.: "Malignant myoepithehoma of the vulva resembling a rhabdoid tumor". Histopathology, 1999; 35, 50.

[11] Perrone T., Swanson P. E., Twiggs L. et al.: "Malignant rhabdoid tumor of the vulva : is distinction from epithelioid sarcoma possible?". Am. J. Surg. Pathol., 1989, 13, 848.

[12] Gururangan S., Bowman L., Parham D. et al.: "Primary extracranial rhabdoid tumors". Cancer, 1993, 71, 2653.