Article Data

  • Views 1232
  • Dowloads 125

Case Reports

Open Access

Vascular tumors of the female genital tract: a clinicopathological study of nine cases

  • A. Kondi-Pafiti1,*,
  • E. Kairi-Vassilatou1
  • H. Spanidou-Carvouni1
  • K. Kontogianni1
  • K. Dimopoulou1
  • K. Goula1

1Pathology Department, Areteion University Hospital, Athens Medical School, Athens, Greece

DOI: 10.12892/ejgo20030148 Vol.24,Issue 1,January 2003 pp.48-50

Published: 10 January 2003

*Corresponding Author(s): A. Kondi-Pafiti E-mail:

Abstract

The aim of this study was to investigate the clinicopathological features of nine unusual vascular tumors of the female genital tract and to investigate the problems in the differential diagnosis from other genital lesions.

Material-methods: In a review of 15,000 specimens of the female genital system examined in our Laboratory during the last decade, nine cases of vascular tumors were found.

Results: A capillary hemangioma of the endometrium, one capillary and one cavernous hemangioma of the cervix, six vulva lesions (one capillary, and one cavernous hemangioma and four angiokeratomas) and one hemangiosarcoma of the mons pubis in a 76-year-old patient were diagnosed.

Conclusions: The differential diagnosis of the vascular tumors must be made mainly from endometriotic lesions and melanomas. Immunohistochemistry (S-100, CD31, CD34, CKS, EMA) aid in the diagnosis. Local excision is adequate for the benign vascular lesions.

Keywords

Hemangioma; Angiosarcoma; Female genital tract; Angiokeratoma

Cite and Share

A. Kondi-Pafiti,E. Kairi-Vassilatou,H. Spanidou-Carvouni,K. Kontogianni,K. Dimopoulou,K. Goula. Vascular tumors of the female genital tract: a clinicopathological study of nine cases. European Journal of Gynaecological Oncology. 2003. 24(1);48-50.

References

[1] Edgerton M. T., Hiebert J.M.: "Vascular and lymphatic tumors in infancy, childhood and adulthood: Challenge of diagnosis and treatment". Curr. Prob. Cancer, 1978, 7, 1

[2] MacCollum D. W.,M artin L. W.: "Hemangioma in infancy and childhood. A report based on 6479 cases". Surg. Clin. No. Am., 1956, 36, 1647.

[3] Lasser A. E., Stein A. F.: "Steroid treatment of hemangiomas in children". Arch. Dermatol., 1976, 163, 517.

[4] Edgerton M. T.:'The treatment of hemangiomas with special reference to the role of steroid therapy". Ann. Surg., 1976, 163, 517.

[5] Gerbie A. B., Hirsch M. R., Greene R. R.: "Vascular tumors of the female genital tract". Obstet. Gynecol., 1955, 6, 499.

[6] Mark R., Poen J., Tran L., Fu Y., Juillard G.: "Angiosarcoma: a report of 67 patients and a review of the literature". Cancer, 1996, 77, 2400.

[7] Rosenberg S. A., Herman D. J., Laurence H.B.: "Sarcomas of soft tissue". In: DeVita V. T., Hellman S., Rosenberg S. A. (eds.): "Cancer: Principles and Practice of Oncology", Philadelphia,J. B Lippincott, 1984, 1243.

[8] Girard C.. Johnson W., Graham J.: "Cutaneous angiosarcoma" Cancer, 1970, 4, 868.

[9] Talerman A.: "Hemangiomas of the ovary and the uterine cervix". Obstet. Gynecol., 1967, 30, 108.

[10] Buscema J., Rosenshein N., Taqi F., Woodruff D.: "Vaginal Hemangiopericytoma: a histopathologic and ultrastructural evalnation". Obstet. and Gynecol., 1985, 66, 82.

[11] Kela K., Aurora A. L.: "Hemangioma of the ovary". J. Indian Med. Assoc., 1980, 75, 201.

[12] Boley S. J., Morse W. E.: "Hormonally influenced hemangiomas" Arch. Surg., 1957, 74, 482.

[13] Cohen P., Young A., Tovell H.: "Angiokeratoma of the vulva: diagnosis and review of the literature". Obstet. and Gynecol., 1989, 44, 339.

[14] Nanus D., Kelsen D., Clark D.: "Radiation-Induced ang1osarcoma". Cancer, 1987, 60, 777.

[15] Maddox J. C., Evans H. L.: "Angiosarcoma of skin and soft tissue: A study of forty-four cases". Cancer, 1981, 48, 1907.

[16] Chen T. K., Hoffman K. D., Hendricks E. J.: "Angiosarcoma following therapeutic irradiation". Cancer, 1979, 44, 2044.

[17] Paik H. H., Komorowski R.: "Hemangiosarcoma of the abdominal wall following irradiation therapy of endometrial carcinoma". Am. J. Clin. Pathol., 1976, 66, 810.

[18] Davies J. D., Rees G. J. G., Mera S. L.: "Angiosarcoma in irradiated post-mastectomy chest wall". Histopathology, 1983, 7, 947.

[19] Karpeh M. S., Caldwell C., Gaynor J. J., Hajdu S. I.,B rennan M F.: "Vascular soft-tissue sarcomas: an analysis of tumor-related mortality". Arch. Surg., 1991, 126, 1474.

Submission Turnaround Time

Top