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Carcinosarcoma of the breast: report of two cases

  • J. Gogas1
  • E. Kouskos1,*,
  • C. Markopoulos1
  • D. Mantas1
  • Z. Antonopoulou1
  • K. Kontzoglou1
  • J. Stamoulis1
  • V. Kyriakou1

12nd,, Department of Propedeutic Surgery - Athens University Medical School - "Laiko" General Hospital - Athens, Greece

DOI: 10.12892/ejgo20030193 Vol.24,Issue 1,January 2003 pp.93-95

Published: 10 January 2003

*Corresponding Author(s): E. Kouskos E-mail:

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Abstract

Carcinosarcoma is a rare, malignant tumor of the breast, consisting of intraductal or infiltrating carcinoma contiguous or subtly merged with a highly cellular, mitotically active pleomorphic spindle cell stroma (sarcoma). It is a form of the metaplastic mammary carcinomas and it is probably derived of myoepithelial cells. We report two cases of breast carcinosarcoma in two white women. The patients, following a frozen section positive for malignancy, had had a modified radical mastectomy. Paraffin sections and positive immunohistochemical cell staining (in our first case) confirmed the diagnosis of carcinosarcoma. This tumor should be distinguished from other forms of metaplastic carcinomas because it is very aggressive and has an ominous prognosis.

Keywords

Carcinosarcoma; Metaplastic Carcinoma; Mammary Gland

Cite and Share

J. Gogas,E. Kouskos,C. Markopoulos,D. Mantas,Z. Antonopoulou,K. Kontzoglou,J. Stamoulis,V. Kyriakou. Carcinosarcoma of the breast: report of two cases. European Journal of Gynaecological Oncology. 2003. 24(1);93-95.

URL:

https://www.ejgo.net/articles/10.12892/ejgo20030193

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