Article Menu

Export Article

More by Authors Links

Article Data

  • Views 1155
  • Dowloads 151

Original Research

Open Access

Immunopathological study of mesonephric lesions of cervix uteri and vagina

  • A. Kondi-Pafitis1,*,
  • E. Kairi1
  • K. I. Kontogianni1
  • C. Dimopoulou1
  • K. Sikiotis1
  • V. Smyrniotis1

1Pathology Laboratory and 2"d Clinic of Obstetrics and Gynecology, Areteion University Hospital, Athens Medical School, Athens, Greece

DOI: 10.12892/ejgo200302154 Vol.24,Issue 2,March 2003 pp.154-156

Published: 10 March 2003

*Corresponding Author(s): A. Kondi-Pafitis E-mail:

PDF (2.16 MB) View Full-text

Abstract

Seventeen cases of mesonephric cervical remnants, four cases of mesonephric cervical carcinoma and nine vaginal Gardner cysts were studied by histochemical and immunohistochemical methods for the presence of mucin, proteoglucans, glucogen, CEA, cytokeratins, secretory component and vimentin. Mesonephric lesions in contrast to endocervical glandular lesions are negative for mucin, glucogen, CEA, and secretory component and positive for vimentin, and broad spectrum cytokeratins. Mesonephric carcinomas present certain immunopathological characteristics that permit their identification and proper treatment.

Keywords

Cervix mesonephric lesions vagina; Gardner cysts

Cite and Share

A. Kondi-Pafitis,E. Kairi,K. I. Kontogianni,C. Dimopoulou,K. Sikiotis,V. Smyrniotis. Immunopathological study of mesonephric lesions of cervix uteri and vagina. European Journal of Gynaecological Oncology. 2003. 24(2);154-156.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200302154

References

[1] Moore K. L.: "The urogenital system". In: "The Developing Human". Philadelphia, Saunders, 1988.

[2] Shah K. H., Kurman R. J., Scully R. E., Norris H. J.: "Atypical hyperplasia of mesonephric remnants in the cervix". Lab. Invest., 1980, 42, 149.

[3] Fu V. S., Reagan J. W.: "Pathology of the uterine cervix, vagina and vulva". Major Problems in Pathology Series, vol. 21, Philadelphia ed. Bennington J.L., Saunders Co., 1989.

[4] Coleman D. C., Evans D. M. D.: "Biopsy Pathology and Cytology of the cervix". London, Chapman and Hall Med. Pub., 1988.

[5] Dallenbach-Hellweg G., Pulsen H.: "Histopathology of Cervix Uteri". Springer-Verlag, 1990, Berlin-New York.

[6] Rosen Y., Dolan T. E.: "Carcinoma of the cervix with cylindromatous features believed to arise in mesonephric duct". Cancer, 1975, 36, 1739.

[7] Ferry J. A., Scully R. E.: "Mesonephric remnants, hyperplasia and neoplasia in the uterine cervix. A study of 49 cases". Am. J. Surg. Pathol., 1990, 14, 1 100.

[8] Clement P. B., Yourg R.H., Keh P.: "Malignant mesonephric neoplasms of the uterine cervix. A report of 8 cases including four with a malignant spindle cell component". Am. J. Surg. Pathol., 1995, 19, 1158.

[9] Blaustein's Pathology of the Female Genital Tract. Robert J. Kurman, (ed.) New York, Springer-Derian, 2002.

Submission Turnaround Time

Top