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Original Research

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Supraclavicular nodal relapse of breast cancer: Prevalence, palliation, and prognosis

  • F. L. Ampil1,*,
  • G. Caldito2
  • B. D. L. Li3
  • G. V. Burton4

1Departments of Radiology, USA

2Departments of Biometry, USA

3Departments of Surgery, USA

4Departments of Medicine, Louisiana State University Health Sciences Center, Shreveport, Louisiana, USA

DOI: 10.12892/ejgo200303233 Vol.24,Issue 3-4,July 2003 pp.233-235

Published: 10 July 2003

*Corresponding Author(s): F. L. Ampil E-mail:

Abstract

Purpose: To determine the frequency, palliative effects of radiotherapy (RT) and survival of patients developing supraclavicular nodal relapse (SNR) after definitive surgery for non-disseminated breast cancer (BCa).

Methods: A retrospective study of individuals treated by breast conserving surgery or modified radical mastectomy for Stage I to III BCa at a single institution during a 17-year period (1980-96) was undertaken.

Results: Of the 536 patients studied, 22 (4%) developed SNR. Among the seven symptomatic women, the complete subjective response rate after RT was 71%. Of the 18 evaluable patients with manifest SNRs, tumor regression was complete in 12 (66.6%), partial in one (5.6%), and absent in five (27.8%). The overall median survival was 11.5 months; five patients (23%) survived for at least two years.

Conclusion: Supraclavicular nodal relapse in breast cancer patients occurs infrequently. The application of radiotherapy for palliation of SNR was fully justified by the perceived results even though long-term survival was not often observed.

Keywords

Breast cancer; Lymph node; Radiotherapy; Palliation

Cite and Share

F. L. Ampil,G. Caldito,B. D. L. Li,G. V. Burton. Supraclavicular nodal relapse of breast cancer: Prevalence, palliation, and prognosis. European Journal of Gynaecological Oncology. 2003. 24(3-4);233-235.

References

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