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Original Research

Open Access

Accuracy of endometrial biopsy with the Cornier pipelle for diagnosis of endometrial cancer and atypical hyperplasia

  • F. Machado1,*,
  • J. Moreno2
  • M. Carazo1
  • J. León3
  • G. Fiol4
  • R. Serna1

1Department of Obstetrics and Gynecology, Hospital Comarcal de/ Noroeste, Caravaca de la Cruz, Murcia, Spain

2Department of Pathology, Hospital Comarcal de/ Noroeste, Caravaca de la Cruz, Murcia, Spain

3Department of Pharmacy, Hospital Morales Meseguer, Murcia, Spain

4Department of Obstetrics and Gynecology, Hospital Torrectirdenas, Almerfa, Spain

DOI: 10.12892/ejgo200303279 Vol.24,Issue 3-4,July 2003 pp.279-281

Published: 10 July 2003

*Corresponding Author(s): F. Machado E-mail: '

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Abstract

Objective: To establish the accuracy of endometrial biopsy with the Cornier pipelle in the diagnosis of endometrial cancer and atypical endometrial hyperplasia in our milieu.

Material and method: We reviewed 1,535 anatomopathologic reports on endometrial biopsies taken from outpatients using the Cornier pipelle between 1997 and 2000, in pre- and postmenopausal patients with abnormal vaginal bleeding. In 168 patients (10.9%), curettage and/or hysterectomy was subsequently carried out. In these cases, the anatomopathologic reports were compared to determine sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and likelihood ratio (LR).

Results: Sensitivity was 84.2%, specificity was 99.1%, accuracy was 96.9%, PPV was 94.1%, NPV was 93.7% and LR was 93.5. In 249 cases (16.09%) the material was insufficient for study.

Conclusion: We determined that endometrial biopsy taken with the Cornier pipelle is, as we practice it, an accurate method for diagnosis of endometrial cancer and its precursor, atypical hyperplasia.

Keywords

Endometrial cancer; Atypical hyperplasia; Endometrial biopsy; Cornier pipelle; Abnormal uterine bleeding

Cite and Share

F. Machado,J. Moreno,M. Carazo,J. León,G. Fiol,R. Serna. Accuracy of endometrial biopsy with the Cornier pipelle for diagnosis of endometrial cancer and atypical hyperplasia. European Journal of Gynaecological Oncology. 2003. 24(3-4);279-281.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200303279

References

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