Title
Author
DOI
Article Type
Special Issue
Volume
Issue
Malignant vulvar melanoma: Colposcopic evaluation and review of the literature. A case report
1Department of Obstetrics and Gynaecology, Italy
2Department of Anatomopathology, University of L'Aquila, Italy
*Corresponding Author(s): L. Di Stefano E-mail:
Because of the rarity of this kind of vulvar neoplasia, the diagnostic difficulties (clinical and histopathological) conditioning the therapeutic approach and the missing iconographical material, we report a case of vulvar melanoma seen at the Department of Obstetrics and Gynecology of the University of L'Aquila in April 2001, together with a review of the literature. Owing to radical vulvectomy and bilateral inguinal lymphadenectomy with the Byron three-incision approach the histological report was: epithelioid cell apigmented melanoma radially spreading (MMSS), a tumor-free margin of at least 1.7 cm with sufficient lympholitic infiltration.
Vulvar melanoma; Colposcopy; Lymphadenectomy
L. Di Stefano,G. Calvisi,G. Coppola,F. Patacchiola,C. Di Berardino,G. Mascaretti. Malignant vulvar melanoma: Colposcopic evaluation and review of the literature. A case report. European Journal of Gynaecological Oncology. 2003. 24(6);523-526.
[1] Dunton CJ., Kautzky M ., Hanau C.: "Malignant melanoma of the vulva: A review". Obstet. Gynecol. Survey, 1995, 50, 739.
[2] Scheistroen M ., Trope C., Koern J., Pettersen E.O., Abeler V.M.: "Malignant melanoma of the vulva: Evaluation of prognostic factors with emphasis on DNA - ploidy in 75 patients". Gynecol Oncol., 1995, 75, 72.
[3] Morrow C.P., Disaia P.J.: "Malignant Melanoma of the female genitalia: A clinical analysis". Obstet. Gynecol. Survey, 1976, 31, 233 .
[4] Fuller P.N.: "Malignant melanoma of the ovary and exposure to clomiphene citrate: a case report an review of the literature". Am. J. Obstet. Gynecol., 1999, 180, 1499.
[5] Phillips G.L., Twiggs L.B., Okagaki T.: "Vulvar melanoma: a microstaging study". Gynecol. Oncol., 1982, 14, 80.
[6] Bradgate M .G., Rollanson T.P., McConkey C.C., Powell J.: "Malignant melanoma of the vulva: a clinico-pathological study of 50 women". Br. J. Obstet. Gynecol., 1990, 97, 124.
[7] Morrow C.P., Rutledge F.N.: "Melanoma of the vulva". Obstet. Gynecol., 1972, 39, 745.
[8] Breslow A.: "Thickness, cross-sectional areas and depth of mvasion in the prognosis of cutaneous melanoma". Ann. Surg., 1970, 172, 902.
[9] Weinstock M.A.: "Malignant melanoma of the vulva and vagma in the United States: Patterns of incidence and population-based estimates of survival". Am. J. Obstet Gynecol., 1994, 171, 1225.
[10] Hacker N.F., Berek J.S., Lagasse L.D. et al.: "Management of regional lymph nodes and their prognostic influence in vulvar cancer". Obstet. Gynecol., 1993, 58, 574.
[11] Phillips GI., Bundy B.N., Okagaki T., Kucera P.R., Stehman F.B.: "Malignant melanoma of the vulva treated by radical hemivulvectomy". Cancer, 1994, 73, 2626.
[12] Morton D.L., Wen D.R., Wong J.H., Economy J.S., Cagle L.A., Storm F.K. et al.: "Technical details of intraoperative lymphatic mapping for early stage melanoma". Arch. Surg., 1992, 127, 392.
[13] Nieweg O.E., Jansen L., Valdes Olmos R.A.: "Lymphatic mappmg and sentinel lymph node biopsy in breast cancer". Eur. J. Nucl. Med., 1999, 26 (suppl. 4), S 11.
[14] De Cesare S.L., Fiorica J.V., Roberts W.S.: "Intraoperative lymphoscintigraphy for the identification of sentinel lymphonodes in vulvar cancer". Gynecol. Oncol., 1997, 66, 28.
Top