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Open AccessBreast cancer metastatic to the vulva after local recurrence occurring on a rectus abdominis myocutaneous flap: A case report and review of the literature
Breast cancer metastatic to the vulva after local recurrence occurring on a rectus abdominis myocutaneous flap: A case report and review of the literature
1Department of Obstetrics and Gynecology, Italy
2Department of Pathology, University of Genoa, San Martino Hospital, Genoa, Italy
*Corresponding Author(s): M. Valenzano Menada E-mail:
Abstract
Introduction: Vulvar metastases are the third largest group of malignant tumors of the vulva. We report the tenth case of breast cancer vulvar metastases arising 11 years after the primary diagnosis of breast ductal carcinoma and the first occurring eight years after a local recurrence on a rectus abdominis myocutaneous flap.
Case report: A 49-year-old woman presented with a voluminous lump of the left labium majus and enlargement of the ipsilateral inguinal lymph nodes. The mass was removed together with the ipsilateral inguinal lymph nodes. Microscopic evaluation of the removed lump revealed massive carcinomatous infiltration. No in situ lesions nor normal breast tissue were identified.
Conclusions: Unusual breast cancer metastases sites should not be ruled out. Our case differs from the preceding cases because this patient underwent plastic surgery with reconstruction of the breast with a rectus abdominis myocutaneous flap one year after mastectomy and developed a local recurrence three years thereafter. It can be hypothesized that lymphatic spread through newly formed lymphatics occurred.
Keywords
Vulvar metastases; Breast carcinoma; Myocutaneous flap; Lymphatic spread
Cite and Share
M. Valenzano Menada,A. Papadia,P. Lorenzi,E. Fulcheri,N. Ragni. Breast cancer metastatic to the vulva after local recurrence occurring on a rectus abdominis myocutaneous flap: A case report and review of the literature. European Journal of Gynaecological Oncology. 2003. 24(6);577-579.
References
[1] Covington E.E., Brendle W.K.: "Breast carcinoma with vulvar metastasis". Obstet. Gynecol., 1964, 23, 910.
[2] Dehner LP.: "Metastatic and secondary tumors of the vulva". Obstet. Gynecol., 1973, 42 (1), 47.
[3] Mader M.H., Friedrich E.G. Jr.: "Vulvar metastasis of breast carcinoma. A case report". J. Reprod. Med., 1982, 27 (3), 169.
[4] Cohen R., Margolius K.A., Guidozzi F.: "Non-gynaecological metastases to the vulva and vagina". S. Afr. Med. J., I 988, 6, 73(3), 159.
[5] Patsner B.: "Bartholin's gland metastases from breast cancer: A case report". Eur. J. Gynaecol. Oncol., 1996, 17 (2), 96.
[6] Curtin W.M., Murthy B.: "Vulvar metastasis of breast carcinoma. A case report". J. Reprod. Med., 1997, 42 (1), 61.
[71 Menzin A.W., De Risi D., Smilari T.F., Kalish P.E., Vinciguerra V.: "Lobular breast carcinoma metastatic to the vulva: A case report and literature review". Gynecol. Oncol., 1998, 69 (1), 84.
[8] Sindico R., Mariani L., Atlante M., Vincenzoni C., Tulini R., Benevolo M.: "Vulvar metastasis from breast carcinoma: A case report and review of the literature". Eur. J. Gynaecol. Oncol., 1998, 19 (4), 386.
[9] Miliaras D.: "Breast-like cancer of the vulva: primary or metastatic? A case report and review of the literature". Eur. J. Gynaecol. Oneal., 2002, 23 (4), 350.
[10] Lee Y.T.: "Breast carcinoma: pattern of metastasis at autopsy". J Surg. Oncol., 1983, 23 (3), 175.
[11] Radnot M., Varga M.: "Metastatic tumor of the orb旷．Ann. Ophthalmo/.,1975, 7 (11), 1465.
[12] Hirshberg A., Buchner A.: "Metastatic tumours to the oral region An overview". Eur. J. Cancer B. Oral. Oncol., 1995, 31 B (6), 355.
[13] Sanchez Aniceto G., Garcia Penin A., de la Mata Pages R., Montalvo Moreno J.J.:'Tumors metastatic to the mandible: analysis of nine cases and review of the literature". J. Oral. Maxillofac. Surg., 1990, 48 (3), 246.
[14] Irvin W.P., Cathro H.P., Grosh W.W., Rice L.W., Andersen W.A.: "Primary breast carcinoma of the vulva: a case report and literature review". Gynecol. Oncol., 1999, 73 (1), 155.
[15] Rose P.G., Roman L.D., Reale F.R., Tak W.K., Hunter R.E.: "Primary adenocarcinoma of the breast arising in the vulva" Obstet. Gynecol., 1990, 76 (3 Pt 2), 537.
[16] Robbins G.F., Berg J.W.: "Bilateral primary breast cancers" Cancer, 1964, 17, 1501.
[17] Porzio G., Ficorella C., Calvisi G., Paris I., Ricevuto E., Marchetti P.: "Ductal breast carcinoma metastatic to the vulva: A case report". Eur. J. Gynaecol. Oncol., 2001, 22 (2), 147.
[18] Miliaras D.: "Breast-like cancer of the vulva: primary or metastatic? A case report and review of the literature". Eur. J. Gynaecol Oncol., 2002, 23 (4), 350.
[19] Slavin S.A., Van den Abbeele A.O., Losken A., Swartz M.A., Jam R.K.: "Return of lymphatic function after flap transfer for acute lymphedema". Ann. Surg., 1999, 229 (3), 421.
[20] Hosal N., Turan E., Aras T.: "Lymphoscintigraphy in pectorahs major myocutaneous flaps". Arch. Otolaryngol. Head Neck Surg., 1994, 120 (6), 659.
[21] Noone R.B., Frazier T.G., Noone G.C., Blanchet N.P., Murphy J.B., Rose D.: "Recurrence of breast carcinoma following immediate reconstruction: a 13-year review". Plast. Re cons tr. Surg., 1994, 93 (I), 96.
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