Article Data

  • Views 1220
  • Dowloads 129

Case Reports

Open Access

Primary leiomyosarcoma of the fallopian tube: A case report

  • L. Mariani1,*,
  • M. Quattrini1
  • M. Galati1
  • B. Dionisi1
  • G. Piperno2
  • F. Modafferi1
  • C. Sbiroli1

1Department of Gynecological Oncology, Italy

2Laboratory of Anatomo-Pathology, Regina Elena National Cancer Institute of Rome, Italy

DOI: 10.12892/ejgo200503333 Vol.26,Issue 3,May 2005 pp.333-335

Published: 10 May 2005

*Corresponding Author(s): L. Mariani E-mail:

Abstract

A primary leiomyosarcoma (LMS) arising from the left fallopian tube in a perimenopausal 48-year-old woman is reported. Primary tubal LMS is an uncommon, exceedingly rare neoplasm, accounting for only a few reported cases so far. To our knowledge, the present case is the 17th tubal LMS reported in the English-language literature. The diagnosis is usually made at the time of laparotomy for a pelvic or adnexal mass or other gynaecological indications. As in ovarian neoplasms, the mainstay of treatment is represented by debulking surgery consisting of total abdominal hysterectomy, bilateral salpingo-oophorectomy, random biopsies, peritoneal washing and excision of all the abdominal tumour masses. Although the approach is radical, the clinical behaviour is very poor. The role of adjuvant radio- or chemotherapy still remains unsolved.

Keywords

Leiomyosarcoma; Mixed mesodermal tumour; Ovarian and fallopian tube neoplasm; Treatment

Cite and Share

L. Mariani,M. Quattrini,M. Galati,B. Dionisi,G. Piperno,F. Modafferi,C. Sbiroli. Primary leiomyosarcoma of the fallopian tube: A case report. European Journal of Gynaecological Oncology. 2005. 26(3);333-335.

References

[1] DiSaia P.J., Pecorelli S.: " Gynecological sarcomas". Semin. Surg Oneal., 1994, 10, 369.

[2] Fowler J., Nathan L., Nieberg R., Berek J.: "Mixed mesodermal sarcoma of the ovary in a young patient: case report". Eur. J Obstet. Gynecol. Reprod. Biol., 1996, 65, 249.

[3] Shakfeh S.M., Woodruff J.D.: "Primary ovarian sarcomas: report of 46 cases and review of the literature". Obstet. Gynecol. Surv., 1987, 42, 331.

[4] Hanjani P., Peterson S.E., Lipton S.E., Nolte J.A.: "Malignamt mixed mesodermal tumours and carcinoma of the ovary: reported 8 cases and review of the literature". Obstet. Gynecol. Surv., 1988, 38, 537.

[5] Holst N., Erichsen A.: "Mixed mesodermal tumor of the fallopian tube". Ann. Chir. Gynaecol., 1981, 70, 207.

[6] Kahanpa K.V., Laine R., Saksela E.: "Malignant mixed mullenan tumor of the fallopian tube". Gynecol. Oneal., 1983, 16, 144.

[7] Buchino J.J., Buchino J.J.: "Malignant mixed mullerian tumor of the fallopian tube". Arch. Patal. Lab. Med., 1987, 111, 386.

[8] Vinker D.A., Mantell B.S., Greenstein R.J.: "Carcinosarcoma of the fallopian tube". Br. J. Obstet. Ginecol., 1980, 87, 530.

[9] O'Toole R.V., Tuttle S.E., Saha N.T.: "Heterologous carcinosarcoma of the fallopian tube". J. Reprod. Med., 1982, 27, 749.

[10] Muntz H.G., Rutgers J.L., Tarraza H.M.. Fuller A.F.: "Carcinosarcomas and mixed mullerian tumours of the fallopian tube" Gynecol. Oneal., 1989, 34, 109.

[11] Jacoby A.F., Fuller A.F., Thor A.N., Muntz H.G.: "Case report primary leiomyosarcoma of the fallopian tube". Gynecol. Oneal., 1993, 51, 404.

[12] FIGO Fallopian tube staging: Acta Obstet. Gynecol. Scand., 1992, 71, 224.

[13] Senger E.: "Ueber ein primaeres sarkom der tuben Centralbl".f Gynaek., 1886, 10, 601.

[14] Dodd W.E.: "Sarcoma of the fallopian tube". Surg. Gynecol Obstet., 1924, 39, 302.

[15] Scheffey L., lang W., Nuggent F.: "Clinical and pathologic aspects of primary sarcoma of the uterine tube". Am. J. Obstet. Gynecol., 1941, 52, 904.

[16] Abrams J., Kazal H., Hobbs R.: "Primary sarcoma of the fallopian tube". Am. J. Obstet. Gynecol., 1958, 75, I 80

[17] Washio T., Akahori W., Hayashi W.: "Case report: Pnmary sarcoma of the fallopian tube". Kobe J. Med. Sci., 1967, 13, 243.

[18] Blarkley J.B.: "Sarcoma of the fallopian tube". J. Obstet Gynaecol. Br. Commonw, 1973, 80, 759.

[19] Harlow B., Weiss N., Lofton S.:'The epidemiology of sarcomas of the uterus". J. Natl. Cancer Inst., 1986, 76, 399.

[20] Takemori M., Nishmura R., Yasuda D., Sugimura K.: "Carci-nosarcoma of the uterus: magnetic resonance imaging". Gynaec Obstet. Invest., 1997, 43, 139.

[21] Major F., Blessing J., Silverberg S., Morrow C., Creasman W., Brady M.: "Prognostic factors in early stage uterine sarcoma. A Gynecologic Oncology Group study". Cancer, 1993, 71, 1702.

[22] Evans H., Chwala S., Simpson C., Finn K.: "Smooth muscle neoplasms of the uterus other than ordinary leiomyoma". Cancer, 1988, 62, 2239.

[23] Schink J.C., Lurain J.R.: " Rare gynecologic malignancies". Curr. Opin. Obstet. Gynecol., 1991, 3, 78.

[24] Rose P., Piver M, Tsukada Y.: "Fallopian tube cancer. T he Roswell Park experience". Cance,; 1990, 66, 2661

[25] Morrow C., d'Ablaing G., Brady L., Blessing J.: "A clinical and pathologic study of 30 cases of malignant mixed mullerian epithelial and mesenchimal ovarian tumors: a Gynecologic Oncology Group study". Gynecol. Oneal., 1984, 18, 278.

[26] Piura B.. Rabinovich A., Yanai-Inbar I., Cohen Y., Glezerman M "Primary sarcoma of the ovary: report of five cases and review of the litterature". Eur. J. Gynecol. Oncol., 1998, 19, 257.

[27] Monk B., Nieberg R., Berek J.: "Primary leiomyosarcoma of the ovary in a perimenarchal female". Gynecol. Oneal., 1993, 48, 389.

[28] Carlson J.A., Day T.G.: "Five-year survival following combination radiotherapy and chemotherapy for mixed mesodermal sarcoma of the ovary". Gynecol. Oneal., 1985, 22, 129.

[29] Pastner B., Greenberg S.: "Mesna, doxorubicin, ifosfamide, and dacarbazine chemotherapy for ovarian mixed mullerian sarcoma: report of four cases". Gynecol. Oneal., 1995, 58, 386.

[30] Piura B., Rabinovich A.: "Primary carcinoma of the fallopian tube study of 11 cases". Eur. J. Obstet. Gynecol. Reprod. Biol., 2000, 91, 169.

Submission Turnaround Time

Top