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Biphasic sarcomatoid carcinoma or carcinosarcoma of the breast: prognosis and therapy

  • J. Cornette1
  • W. A. A. Tjalma1,*,
  • P. Buytaert1

1Department of Gynaecology and Gynaecological Oncology, University Hospital Antwerp, Edegem, Belgium

DOI: 10.12892/ejgo200505514 Vol.26,Issue 5,September 2005 pp.514-516

Published: 10 September 2005

*Corresponding Author(s): W. A. A. Tjalma E-mail:

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Abstract

Biphasic sarcomatoid carcinoma of the breast represents only 0.2% of all breast cancer. Due to its rarity and repetitive reclassifications little is known about optimal treatment modalities. These tumours form a diagnostic and therapeutic challenge. The present report describes our experience with a case of biphasic sarcomatoid carcinoma of the breast and a review of the relevant literature is discussed.

Keywords

Biphasic sarcomatoid carcinoma; Carcinosarcoma; Breast cancer; Prognosis; Treatment

Cite and Share

J. Cornette,W. A. A. Tjalma,P. Buytaert. Biphasic sarcomatoid carcinoma or carcinosarcoma of the breast: prognosis and therapy. European Journal of Gynaecological Oncology. 2005. 26(5);514-516.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200505514

References

[1] Gutman H., Pollock R.E., Janjan N.A., Johnston D.A.: "Biologic distinctions and therapeutic implications of sarcomatoid metaplasia of epithelial carcinoma of the breast". J. Am. Coll. Surg., 1995, 180. 193.

[2] Diebold-Berger S., de Roquancourt A.: "Carcinome sarcomatoide du sein". Arch. Anat. Cytol. Pathol.. 1995, 43, 51.

[3] Wargotz E.S., Norris H.J.: "Metaplastic carcinomas of the breast III. Carcinosarcoma". Cancer, 1989, 64, 1490.

[4] Mainguene C., Laporte J.L., Zakhama A., Destable M.D., Amouroux J.: "Carcinosarcoma of the breast. Anatomic-clinical study of a case". Arch. Anat. Cytol. Pathol., 1993, 41, 25.

[5] Gersell D.J., Katzenstein A.L.: "Spidle cell carcinoma of the breast. A clinopathologic and ultrastructural study". Hum. Pathol.. 1981, 12, 550.

[6] Ellis I.O., Bell J., Ronpan J.E., Elston G.W., Blarney R.W "Immunohistochemical investigations of intermediate filament proteins and epithelial membrane antigen in spidle cell tumours of the breast". J. Pathol., 1988, 154, 157.

[7] Tavassoli F.A.: "Classification of metaplastic carcinomas of the breast". Pathol. Annu., 1992, 27. 89.

[8] Foschini M.P, Dina R.E, Eusebi V.: "Sarcomatoid neoplasms of the breast: proposed definitions for biphasic and monophasic sarcomatoid mammary carcinomas". Semin. Diagn. Pathol., 1993, 10, 128.

[9] Pope TL., Fechner R.E., Brenbridge A.N.: "Carcinosarcoma of the breast: radiologic, ultrasonographic, and pathologic correlation". Can. Assoc. Radio!. J., 1987, 38, 50.

[10] Taylor D.B., Adamson R., Minchin D.E., Reading L.: "Carcmoma of the breast with sarcomatous metaplasia". Australas. Radiol., 1994, 38. 262.

[11] Kurian K.M., Al-Nafussi A.: "Sarcomatoid/metaplastic carcinoma of the breast: a clinicopathological study of 12 cases". Histopathology, 2002, 40, 58.

[12] Bolton B., Sieunarine K.: "Carcinosarcoma: a rare tumour of the breast". Aust. NZ. J. Surg., 1990, 6, 917.

[13] Pasternak J.G., Wirth J.E.: "Adeno-acanthoma Sarcomatodes of the mammary gland". Am. J. Pathol., 1936, 12, 423.

[14] Azzopardi J.G.: "Problems in Breast Pathology". Philadelphia, Saunders, 1979, 297.

[15] Flint A., Oberman H.A., Davenport R.D.: "Cytophotometric measurements of metaplastic carcinoma of the breast:correlation with pathologic features and clinical behavior". Mod. Pathol., 1988, 1, 193.

[16] Oberman H.A.: "Metaplastic carcinoma of the breast. A Clinopathology study of 29 patients". Am. J. Surg. Pathol., 1987, 11, 918.

[17] Alexiev B., Popov A.: "Carcinosarcoma of the breast. Immunohistochemical and ultrastructural studies". Zentralbl. Pathol., 1992, 138, 71.

[18] Wargotz E.S, Norris H.J.: "Metaplastic carcinomas of the breast: V. Metaplastic carcinoma with osteoclastic giant cells". Hum Pathol., 1990, 21, 1142.

[19] Wada H., Enomoto T., Tsujimoto M., Nomura T, Murata Y, Shroyer KR.: "Carcinosarcoma of the breast: molecular-biological study for analysis of histogenesis". Hum. Pathol., 1998, 29, 324.

[20] Zhuang Z., Lininger R.A, Man Y.G., Albuquerque A., Merino M.J., Tavassoli F.A.: "Identical clonality of both components of mammary carcinosarcoma with differential loss of heterozygosity". Mod. Pathol., 1997,10, 354.

[21] Teixeira M.R., Qvist H., Bohler P.J., Pandis N., Heim S.: "Cytogenetic analysis shows that carcinosarcomas of the breast are of monoclonal origin". Genes Chroma. Cancer, 1998, 22, 145.

[22] Thompson L., Chang B., Barsky S.H.: "Monoclonal origins of malignant mixed tumors (carcinosarcomas). Evidence for a divergent histogenesis". Am. J. Surg. Pathol., 1996, 20, 277.

[23] Baker R.R.: "Unusual lesions and their management". Surg. Clin North. Am., 1990, 70, 963.

[24] Kuo S.H., Chen C.L., Huang C.S., Cheng A.L.: "Metaplastic carcinoma of the breast: analysis of eight Asian patients with special emphasis on two unusual cases presenting with inflammatory-type breast cancer". Anticancer Res., 2000, 20, 2219.

[25] Harris M., Persaud V.: "Carcinoma of the breast". J. Pathol., 1974, 112, 99.

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