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Gherlin expression in women with polycystic ovary syndrome - a preliminary study

  • J. Skommer1
  • K. Katulski2
  • E. Portba1
  • B. Mtczekalski2,*,
  • R. Slopien2
  • R. Plewa3
  • A. Goidzicka-Józefiak1
  • A. Warenik-Szymankiewicz2

1Department of Molecular Virology, Poznan Adam Mickiewicz University, Poland

2Department of Gynecological Endocrinology, Poznan University of Medical Sciencies, Poland

3Department of Animal Physiology, Poznan Adam Mickiewicz University, Poznan, Poland

DOI: 10.12892/ejgo200505553 Vol.26,Issue 5,September 2005 pp.553-556

Published: 10 September 2005

*Corresponding Author(s): B. Mtczekalski E-mail:

Abstract

The etiology and pathogenesis of polycystic ovary syndrome (PCOS) is still unknown. Using real-time PCR, we detected that polycystic ovaries showed almost ten times lower expression of ghrelin mRNA than normal ovaries, whereas the mRNA levels in blood cells were similar in both study groups. This suggests that the presence of ghrelin in PCOS and normal ovaries may have an autocrine/paracrine modulatory effect on ovary functions and local significance in the etiology of PCOS.

Keywords

Ghrelin expression, PCOS

Cite and Share

J. Skommer,K. Katulski,E. Portba,B. Mtczekalski,R. Slopien,R. Plewa,A. Goidzicka-Józefiak,A. Warenik-Szymankiewicz. Gherlin expression in women with polycystic ovary syndrome - a preliminary study. European Journal of Gynaecological Oncology. 2005. 26(5);553-556.

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