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Molecular markers of miscellaneous primary and metastatic tumors of the uterine cervix S.

  • S.C. Chauhan1
  • D. Kumar2
  • M.C. Bell1
  • M.D. Koch3
  • M. Verma4,*,

1Cancer Biology Research Institute, South Dakota Health Research Foundation and Department of Obstetrics and Gynecology, USA

2Department of Biological and Environmental Sciences, University of the District of Columbia, Washington, USA

3Department of Laboratory Medicine, Sanford School of Medicine, the University of South Dakota, USA

4Analytic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA

DOI: 10.12892/ejgo20070105 Vol.28,Issue 1,January 2007 pp.5-14

Published: 10 January 2007

*Corresponding Author(s): M. Verma E-mail:

Abstract

Miscellaneous primary tumors of the uterine cervix are rare. Markers which can be utilized to detect these tumors are very few and in most cases, have not been clinically validated. The information provided in this article will help in developing strategies to discover novel markers and initiate translational research in this ignored area. Based on the reported studies, cytokeratin markers are common in many tumors and few of these rare cancers demonstrate human papilloma-virus (HPV) and Epstein Bar virus (EBY) infection. Due to the very low prevalence of these tumors, epidemiological studies have not been conducted and the etiology of these tumors is largely unknown.

Keywords

Uterine cervix; Rare tumors; Markers; Metastatic

Cite and Share

S.C. Chauhan,D. Kumar,M.C. Bell,M.D. Koch,M. Verma. Molecular markers of miscellaneous primary and metastatic tumors of the uterine cervix S.. European Journal of Gynaecological Oncology. 2007. 28(1);5-14.

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