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Open Access"Occult" neuroendocrine component and rare metastatic pattern in cervical cancer: Report of a case and brief review of the literature
"Occult" neuroendocrine component and rare metastatic pattern in cervical cancer: Report of a case and brief review of the literature
1Department of Obstelrics and Gynecology, University of Cologne School of Medicine, Cologne, Germany
2Depanment of Obstetrics and Gynecology, S1. Elisabeth Hospital, Cologne, Germany
3Departmenl of Radiology, University of Cologne School of Medicine, Cologne, Germany
4Department of Pa1hology, Universi八, of Cologne School of Medicine, Cologne, Germany
5Department of Obstetrics and Gynecology, Florence Nightingale Hospital, Diisseldorf, Germany
*Corresponding Author(s): K. Rhiem E-mail:
Abstract
Distant metastases in small cell carcinomas of the uterine cervix are rare, and a disseminated manifestation of the disease is uncommon. This is a case report of a 40-year-old woman treated with platin-based radio-chemotherapy for a moderately differentiated squamous cell cervical cancer FIGO Stage IB 1 (with positive paraaortic lymph nodes). One year later she presented with remarkably unusual cutaneous metastases of the left thumb and scalp as the first signs of spread of disease, including kidney, lung and brain metastases. An advanced retrospective immunohistochemical staining of the cervical biopsy discovered a small neuroendocrine component of the carcinoma as the presumably causative factor for the rare metastastic pattern and poor prognosis.
Keywords
Cervical Cancer, squamous cell carcinoma, neuroendocrine carcinoma, thumb metastasis, renal metastases, staging lymphadenectomy
Cite and Share
K. Rhiem,M. Possover,A. Gossmann,K. Drebber,P. Mallmann,U. Ulrich. "Occult" neuroendocrine component and rare metastatic pattern in cervical cancer: Report of a case and brief review of the literature. European Journal of Gynaecological Oncology. 2007. 28(2);139-141.
References
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