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Original Research

Open Access

Does the copper intrauterine device affect serum cancer antigen 125 levels?

  • M. KARACA1,*,
  • S. Kumru2
  • N. Dikmeli2

1Department of Obstetrics and Gynecology, Kajkas University Medical Faculty, Kars, Turkey

2Department of Obstetrics and Gynecology'，Furat University Medical Faculty, Elazig, Turkey

DOI: 10.12892/ejgo200706524 Vol.28,Issue 6,November 2007 pp.524-525

Published: 10 November 2007

*Corresponding Author(s): M. KARACA E-mail:

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Abstract

Purpose: This study aimed to reveal the effect of the copper IUD, if any, on serum CA-125 levels in patients who use the device as a contraceptive.

Methods: Blood samples were obtained two times from 20 healthy volunteers before and after IUD insertion, and sera were isolated. The sera, centrifuged at 2000 G and kept at -70 degrees C in a deep freezer until analyzed, were processed for CA-125 levels by the CA-125 kit using VIDAS PC analyzer (Biomerieux, France) and results were compared.

Results: The CA-125 level of the serum obtained from the first blood samples was significantly higher than that of the second sample (24.63 +/- 25.40 mIU/ml and 14.44 +/- 10.08 mIU/ml, respectively) (p < 0.05).

Conclusion: The results of this study indicate that the serum level of CA-125 may be lower in patients using copper IUDs which may be helpful in evaluation of ovarian masses in women in reproductive age.

Keywords

CA-125; Copper IUD

Cite and Share

M. KARACA,S. Kumru,N. Dikmeli. Does the copper intrauterine device affect serum cancer antigen 125 levels? . European Journal of Gynaecological Oncology. 2007. 28(6);524-525.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200706524

References

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[5] Avaliable at URL: http://www.popcouncil.org.

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[8] Finkler N.J., Benecerrat B., Lavin P., Wojciechowski C., Knapp R.C.: "Comparison of serum CA-125, clinical impression and ultrasound in the preoperative evaluation of ovarian masses". Obstet. Gynecol., 1988, 72, 659.

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[10] Turk H.M., Pekdemir H., Buyukberber S., Sevinc A., Camci C., Kocabas R. et al.: "Serum CA-125 levels in patients with chronic heart failure and accompanying pleural fluid". Tumour Biol., 2003, 24, 172.

[11] Karaca M., Gocmen A., Sari A., Ugur M.G.: "Effect of hysterosalpingography on serum cancer antigen (CA-125) levels". Eur. J. Gynaecol. Oncol., 2005, 26, 203.

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