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Original Research

Open Access

Primary ovarian choriocarcinoma mimicking ectopic pregnancy managed with laparoscopy - case report

  • Y.X. Chen1
  • J. Xu2
  • W.G. Lv1
  • X. Xie1,*,

1Department of Gynecologic Oncology, P.R. China

2Department of Reproductive Medicine, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, P.R. China

DOI: 10.12892/ejgo200802174 Vol.29,Issue 2,March 2008 pp.174-176

Published: 10 March 2008

*Corresponding Author(s): X. Xie E-mail: /

Abstract

Nongestational ovarian choriocarcinomas are extremely rare and pose diagnostic challenges in reproductive-aged patients because of elevated human chorionic gonadotrophin (hCG). A 23-year-old nulliparous Chinese woman with nongestational ovarian choriocarcinoma escaped diagnostic testing and was initially treated for an ectopic pregnancy. Three months after her first visit, a diagnostic laparoscopy demonstrated a nongestational ovarian choriocarcinoma. Comprehensive surgical staging was performed by laparoscopy. The tumor was confined to the left ovary. The patient was categorized as FIGO Stage IA. She was given four courses of combined chemotherapy after laparoscopic surgery and has been disease-free for 36 months.

Keywords

Nongestational ovarian choriocarcinoma; Human chorionic gonadotrophin; Laparoscopy; Chemotherapy

Cite and Share

Y.X. Chen,J. Xu,W.G. Lv,X. Xie. Primary ovarian choriocarcinoma mimicking ectopic pregnancy managed with laparoscopy - case report. European Journal of Gynaecological Oncology. 2008. 29(2);174-176.

References

[1] Lai C.H., Chang T.C., Hsueh S., Wu T.I., Chou H.H., Wang P.N.: “Outcome and prognostic factors in ovarian germ cell malignancies”. Gynecol. Oncol., 2005, 96, 784.

[2] Oliva E., Andrada E., Pezzica E., Prat J.: “Ovarian carcinomas with choriocarcinomatous differentiation”. Cancer, 1993, 72, 2441.

[3] Sjovall K., Nilsson B., Einhorn N.: “Different types of rupture of the tumor capsule and the impact on survival in early ovarian carcinoma”. Int. J. Gynecol. Cancer, 1994, 4, 333.

[4] Sainz de la Cuesta R., Goff B.A., Fuller A.F. Jr, Nikrui N., Eichhorn J.H., Rice L.W.: “Prognostic importance of intraoperative rupture of malignant ovarian epithelial neoplasms”. Obetet. Gynecol., 1994, 84, 1.

[5] Yoon G.H., Stein J.P., Skinner D.G.: “Retroperitoneal lymph node dissection in the treatment of low-stage nonseminomatous germ cell tumors of the testicle: an update”. Urol. Oncol., 2005, 23, 168.

[6] Allaf M.E., Bhayani S.B., Link R.E., Schaeffer E.M., Varkarakis J.M., Shadpour P. et al.: “Laparoscopic retroperitoneal lymph node dissection: duplication of open technique”. Urology, 2005, 65, 575.

[7] Spirtos N.M., Eisekop S.M., Boike G., Schlaerth J.B.,Cappellari J.O.: “Laparoscopic staging in patients with incompletely staged cancers of the uterus, ovary, fallopian tube, and primary peritoneum: a Gynecologic Oncology Group (GOG) study”. Am. J. Obstet. Gynecol., 2005, 193, 1645.

[8] Tsujioka H., Hamada H., Miyakawa T., Hachisuga T., Kawarabayashi T.: “A pure nongestational choriocarcinoma of the ovary diagnosed with DNA polymorphism analysis”. Gynecol. Oncol., 2003, 89, 540.

[9] Williams S.D., Blessing J.A., Liao S.Y., Ball H., Hanjani P.: “Adjuvant therapy of ovarian germ cell tumors with cisplatin, etoposide and bleomycin: an adjuvant trial of the Gynecologic Group”. J. Clin. Oncol., 1994, 12, 701.

[10] Gatta G., Ciccolallo L., Kunkler I., Capocaccia R., Berrino F., Coleman M.P., et al.: “Survival from rare cancer in adults: a population- based study”. Lancet Oncol., 2006, 7, 132.

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