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Six-year follow-up without recurrence after a carcinosarcoma of the breast: case report

  • R. Wernert1
  • G. Yazbek2
  • C. Voisin-Rigaud3
  • G. Ducarme4,*,

1Department of Surgical Oncology, Institut Jean Godinot, Reims, France

2Department of Breast Medical Oncology, Institut Jean Godinot, Reims, France

3Department of Pathology, Institut Jean Godinot, Reims, France

4Department of Obstetrics and Gynecology, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris 7, Clichy, France

DOI: 10.12892/ejgo201102226 Vol.32,Issue 2,March 2011 pp.226-227

Published: 10 March 2011

*Corresponding Author(s): G. Ducarme E-mail: guillaume.ducarme@bjn.aphp.fr

Abstract

Carcinosarcoma (CS) of the breast is a rare entity (less than 0.2% of breast malignancies), characterized by the presence of a biphasic pattern of malignant epithelial and mesenchymal elements, and with a high risk of loco-regional recurrence. The diagnosis of CS of the breast is difficult and needs detailed histological investigations to differentiate it from other malignant breast tumors. Expertise and evidence-based information on optimal treatment is very limited due to the low incidence and inconsistent classification. The principles of treatment modalities seem to be similar to others breast malignancies. CS has a different biologic behavior from others breast cancers, being very aggressive in keeping with its high-grade mesenchymal stroma. Still many questions remain about its origin and optimal treatment modalities for better outcome. We report the case of CS of the breast without local or regional recurrence after six years of follow-up in an 82-year-old woman.

Keywords

Breast tumors; Carcinosarcoma; Follow-up

Cite and Share

R. Wernert,G. Yazbek,C. Voisin-Rigaud,G. Ducarme. Six-year follow-up without recurrence after a carcinosarcoma of the breast: case report. European Journal of Gynaecological Oncology. 2011. 32(2);226-227.

References

[1] Tokudome N., Sakamoto G., Sakai T., Sarumaru S., Okuyama N., Hori F. et al.: “A case of carcinosarcoma of the breast”. Breast Cancer, 2005, 12, 149.

[2] Cornette J., Tjalma W.A., Buytaert P.: “Biphasic sarcomatoid carcinoma or carcinosarcoma of the breast: prognosis and therapy”. Eur. J. Gynaecol. Oncol., 2005, 26, 514.

[3] Wargotz E.S., Norris H.J.: “Metaplastic carcinoma of the breast. III. Carcinoma”. Cancer, 1989, 64, 1490.

[4] Wada H., Enomoto T., Tsujimoto M., Nomura T., Murata Y., Shroyer K.R.: “Carcinosarcoma of the breast: molecular-biological study for analysis of histogenesis”. Hum. Pathol., 1998, 29, 1324.

[5] Gogas J., Kouskos E., Markopoulos C., Mantas D., Antonopoulou Z., Kontzoglou K. et al.: “Carcinosarcoma of the breast: report of two cases”. Eur. J. Gynaecol. Oncol., 2003, 24, 93.

[6] Gutman H., Pollock R.E., Janjan N.A., Johnston D.A.: “Biologic distinctions and therapeutic implications of sarcomatoid metaplasia of epithelial carcinoma of the breast”. J. Am. Coll. Surg., 1995, 180, 193.

[7] Hennessy B.T., Giordano S., Broglio K., Duan Z., Trent J., Buchholz T.A. et al.: “Biphasic metaplastic sarcomatoid carcinoma of the breast”. Ann. Oncol., 2006, 17, 605.

[8] Aritas Y., Bedirli A., Karahan O.I., Okten T., Sakrak O., Ince O.: “Carcinosarcoma of the breast: clinicopathologic and radiologic findings in an unusual case”. Breast J., 2003, 9, 323.

[9] Harris M., Persaud V.: “Carcinosarcoma of the breast”. J. Pathol., 1974, 112, 99.

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