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Endometrial polyp harboring a primary B-cell non-Hodgkin lymphoma: a useful in-office hysteroscopic approach

  • U. Indraccolo1,*,
  • R. Ranaldi2
  • M. Mirabile3
  • R. Centurioni3

1Complex Operative Unit of Obstetrics and Gynecology, Hospital of Civitanova Marche, Area Vasta 3, Civitanova Marche, Italy

2Complex Operative Unit of Pathology, Hospital of Macerata, Area Vasta 3, Macerata, Italy

3Complex Operative Unit of Internal Medicine of Civitanova Marche, Area Vasta 3, Civitanova Marche, Italy

DOI: 10.12892/ejgo3070.2016 Vol.37,Issue 4,August 2016 pp.572-574

Published: 10 August 2016

*Corresponding Author(s): U. Indraccolo E-mail: ugo.indraccolo@libero.it

Abstract

A non-menopausal women underwent gynecological evaluation for spotting and menstrual irregularities. After first line gynecological assessments, the patient underwent office hysteroscopy. By using an in-office technique, two isthmic endometrial polyps and one cervical polyp were removed. One endometrial polyp was found to harbor a B-cell high-grade lymphoma just on the apex (found to be necrotic). The following staging examinations and the pathological assessment of the endometrium, the uterus, the adnexa, and the lymphatic regional nodes did not find any localization of the lymphoma. No additional treatments were done. The patient is alive and disease- free at 18 months follow-up.

Keywords

Endometrial polyp; B-cell lymphoma; Hysteroscopy.

Cite and Share

U. Indraccolo,R. Ranaldi,M. Mirabile,R. Centurioni. Endometrial polyp harboring a primary B-cell non-Hodgkin lymphoma: a useful in-office hysteroscopic approach. European Journal of Gynaecological Oncology. 2016. 37(4);572-574.

References

[1] Lagoo A.S., Robboy S.J.: “Lymphoma of the genital tract: current status”. Int. J. Gynecol. Pathol., 2005, 25, 1.

[2] Rittenbach J., Cao J.D., Weiss L.M., et al.: “Primary diffuse large Bcell lymphoma of the uterus presenting solely as an endometrial polyp”. Int. J. Gynecol. Pathol., 2005, 24, 347.

[3] Annibali O., Romeo A.A., Agostinelli C., et al.: “A case of primary MALT lymphoma of the endometrium presenting as an asymptomatic polyp”. Ann. Hematol., 2009, 88, 491.

[4] Xia Y., Wang Y., Jiang Y., et al:. “Primary intravascular large B cell lymphoma of the endometrium”. Acta. Histochem., 2014, 116, 993.

[5] Guldrís E.M., Vázquez P., Fernández A.: “Primary endometrial non- Hodgkin's lymphoma treated by chemotherapy and radiotherapy”. Acta. Obstet. Gynecol. Scand., 2013, 92, 606.

[6] McCluggage W.G.: “Miscellaneous disorders involving the endometrium”. Semin. Diagn. Pathol., 2010, 27, 287.

[7] Ivengar P., Deodhare S.: “Primary extranodal marginal zone B-cell lymphoma of MALT type of the endometrium”. Gynecol. Oncol., 2004, 93, 238.


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