Title
Author
DOI
Article Type
Special Issue
Volume
Issue
Cervical biopsy specimens and human papilloma virus positivity in patients with external genital warts
1Department of Dermatology & Venerology, Turkey
2Department of Pathology, Faculty of Medicine, University of Dicle, Diyarbakir, Turkey
3Department of Obstetrics and Gynecology, Hospital of Government, Diyarbakir, Turkey
*Corresponding Author(s): S. Akdeniz E-mail:
Cervical biopsy specimens were taken from 16 women with external genital warts in order to diagnose concomitant cervical human papillomavirus (HPV) infection and cervical intraepithelial neoplasia (CIN) according to pathology. Positive HPV infection was detected 56% (9/16) of the patients. Among those patients 66% (6/9) had concurrent subclinical low-grade CIN lesions. One of those patients had a high-grade CIN lesion. It is concluded that cervical HPV infection was rather common in women with external genital warts and it is valuable to examine cervical HPV infection by biopsy to detect concomitant CIN.
Human papillomavirus; Cervical intraepithelial neoplasia
S. Akdeniz,M. Yald1z,N. Akdeniz. Cervical biopsy specimens and human papilloma virus positivity in patients with external genital warts. European Journal of Gynaecological Oncology. 2002. 23(5);460-462.
[1] Franco E. L., Villa L. L., Richardson H., Rohan T., Ferenczy A.: "Epidemiology of cervical human papillomavirus infection". In: Franco E. L., Monsonego J., editors. New developments in cervical cancer screening and prevention. Oxford (UK): Blackwell Science, 1997, 14.
[2] Hildesheim A., Schiffman M. H., Gravitt P. E., Glass A. G., Greer C. E., Zhang T. et al.: "Persistence of type-specific human papillomavirus infection among cytologically normal women". J. Infect. Dis., 1994, 169, 235.
[3] Franco E. L., Villa L. L., Sobrinho J.P., Prado J.M., Rousseau M.C., Desy M. et al.: "Epidemiology of acquisition and clearance of cervical human papillomavirus infection in women from a highrisk area for cervical cancer". J. Infect. Dis., 1999, 180, 1415.
[4] Ho G. Y. F.,B urk R. D.,K lein S.,K adish A. S.,C hang C. J.,Palan P. et al.: "Persistent genital human papillomavirus infection as a risk factor for persistent cervical dysplasia". J. Natl. Cancer Inst., 1995, 87, 1365.
[5] Munoz N., Bosch F. X., Desanjose S., Tafur L., Izarzugaza I., Gili M. et al.: "The causal link between human papillomavirus and invasive cervical cancer: a population-based case-control study in Colombia and Spain". J. Int. Cancer, 1992, 52, 743.
[6] Schiffman M. H., Bauer H. M., Hoover R. N., Glass A. G., Cadell D. M., Rush B. B. et al.: "Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia". J. Natl. Cancer Inst., 1993, 85, 958.
[7] Song X. H., Yu X. M., Weng L. J.: "Detection of cervical human papillomavirus infection from women with externalgenital condyloma acuminata". Zhonghua Fu Chan Ke Za Zhi, 1994, 29 (11),673, 700.
[8] Petersen C. S., Thomsen H.K., Sondergaard J.: "Cervical signs of HPV infection in PAP-smear negative women with externalgenital warts". Acta Derm. Venereol., 1989, 69 (5), 454.
[9] Franco E. L.: "Cancer causes revisited: human papillomavirus and cervical neoplasia". J. Natl. Cancer Inst., 1995, 87, 779.
[10] IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans. Vol. 64. Human papillomaviruses. Lyon (France): International Agency for Research on Cancer, 1995.
[11] Koutsky L.: "Epidemiology of genital human papillomavirus infection". Am. J. Med., 1997, 102, 3.
[12] Melkert P. W., Hopman E., van den Brule A. J., Risse E. K., van Dies! P. J., Bieker 0. P. et al.: "Prevalence of HPV in cytomorphologically normal cervical smears, as determined by the polymerase chain reaction, is age-dependent". Int. J. Cancer, 1993, 53, 919.
[13] Burk R. D., Kelly P., Feldman J., Bromberg J., Vermund S. H., Dehovitz J. A. et al.: "Declining prevalence of cervicovaginal human papillomavirus infection with age is independent of other risk factors". Sex. Trans. Dis., 1996, 23, 333.
[14] Wright T. C., Kurman R. J.: "A critical review of the morphologic classification systems of preinvasive lesions of the cervix: the scientific basis for shifting the paradigm". Papillomavirus Rep., 1994, 5, 175.
[15] Hildesheim A., Schiffman M. H., Gravitt P. E., Glass A.G., Greer C. E., Zhang T. et al.: "Persistence of type-specific human papillomavirus infection among cytologically normal women". J. Infect. Dis., 1994, 169, 235.
[16] Petersen C. S., Lindeberg H., Thomsen H. K.: "Human papillomavirus types in cervical biopsy specimens from Pap-smear-negativewomen with external genital warts". Acta Obstet. Gynecol. Scand., 1991, 70 (1), 69.
Web of Science (WOS) (On Hold)
Journal Citation Reports/Science Edition
Google Scholar
JournalSeek
Top