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Vulvar Paget's disease: review of the literature, considerations about histogenetic hypothesis and surgical approaches

  • A. Tinari1
  • S. Pace1
  • M. Fambrini2
  • D. Eleuteri Serpieri3
  • A. Frega1,*,

1Department of Gynaecology, Perinatology and Child Care. Universty of Rome, "La Sapienza", Italy

2Department of Gynaecology, Perinatology and Reproductive Medicine, University of Florence, Italy

3Department of Experimental Medicine and Pathology, University of Rome, "La Sapienza", Italy

DOI: 10.12892/ejgo200206551 Vol.23,Issue 6,November 2002 pp.551-552

Published: 10 November 2002

*Corresponding Author(s): A. Frega E-mail:

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Abstract

Paget's disease of the vulva is a rare neoplasm that occurs on the apocrine glands. It predominantly is an intraepithelial lesion, but has the potential for dermal invasion and on occasion has been associated with an underlying adenocarcinoma.

Keywords

Paget's disease; Vulva; Pruritus; Histogenetic hypothesis


Cite and Share

A. Tinari,S. Pace,M. Fambrini,D. Eleuteri Serpieri,A. Frega. Vulvar Paget's disease: review of the literature, considerations about histogenetic hypothesis and surgical approaches. European Journal of Gynaecological Oncology. 2002. 23(6);551-552.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200206551

References

[1] B. Piura, A. Rabinovich, R. Dgani: "Extramammary Paget's disease of the vulva: report of five cases and review of the literature". Eur. J. Cynaec. Oneal., 1999, 2, 98.

[2] D. A. Popiolek, S. l. Hajdu, D. Gal: "Case report. Synchronous Paget's disease of the vulva and breast". Cynecol. Oneal., 1998, 71, 137.

[3] D. Crawford, M. Nimmo, P. B. Clement, T. Thomson, J. Benedet, D. Miller, G. Blake Gilks: "Prognostic factors in Paget's disease of the vulva: a study of 21 cases". Int. J. Cynecol. Pathol., 1999, 18, 351.

[4] S. Kodama, T. Kaneko, M. Saito, N. Yoshiya, S. Homma, K Tanaka: "A clinicopathologic study of 30 patients w ith Paget's disease of the vulva". Cynecol. On col., 1995, 56, 63.

[5] A. Fishman, S. Lew, M. Altaras,Y. Beyth, J. Bernheim: "A 30s PAS stain for frozen 、ection analysis of surgical margins of vulvectomy in Paget's disease". Eur. J. Cynaecol. Oneal., 1998, 19, 482.

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