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SIADH associated with ovarian immature teratoma: a case report

  • C.M. Lam1,*,
  • V. Shun-yin Yu1

1Department of Obstetrics & Gynaecology, Princess Margaret Hospital, Lai Chi Kok, Kowloon, Hong Kong, SAR, China

DOI: 10.12892/ejgo200401107 Vol.25,Issue 1,January 2004 pp.107-108

Published: 10 January 2004

*Corresponding Author(s): C.M. Lam E-mail:

Abstract

Immature teratoma in association with SIADH is rare. A 17-year-old patient presented with a pelvic mass and serum sodium concentration of 121 mmol/l. Subsequent investigation confirmed SIADH and grade 2 ovarian immature teratoma. No other causes of SIADH were found apart from the immature teratoma. There was no further recurrence of SIADH after the curative surgery and chemotherapy. We postulate that immature teratoma consists of neurohypophyseal structures which account for the ADH release.

Keywords

SIADH; Immature teratoma; Sodium

Cite and Share

C.M. Lam,V. Shun-yin Yu. SIADH associated with ovarian immature teratoma: a case report. European Journal of Gynaecological Oncology. 2004. 25(1);107-108.

References

[1] Rose B. D., Post T. W.: "Hypoosmolal states: hyponatremia". In: Rose B. D., Post T. W. (eds.): "Clinical Physiology of Acid-base and Electrolyte Disorders". New York, McGraw-Hill, 2001, 696.

[2] Schwartz W. B., Bennett W., Curelop S., Bartter F. C.: "A syndrome of renal sodium loss and hyponatraemia probably resulting from inappropriate secretion of ADH". Am. J. Med., 1957, 23, 529.

[3] Sorensen J. B., Andersen M. K., Hansen H. H.: "Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in malignant disease". J. Intern. Med., 1995, 238, 97.

[4] Lam S. K., Cheung L. P.: "Inappropriate ADH secretion due to immature ovarian teratoma". Aust. N. Z. J. Obstet. Gynaecol., 1996, 36, 104.

[5] DiSaia P. J., Creasman W. T.: "Germ cell, stromal, and other ovarian tumors". In: DiSaia P. J., Creasman W. T. (eds.): "Clinical Gynecologic Oncology". 6th ed., St. Louis, Mosby-Year Book, 2002, 351.

[6] Sherbet G. V.: "Similarities between embryonic and neoplastic systems". In: Sherbet G. V. (ed.): "The Biology of Tumour Malignancy". London, Academic Press Inc., 1982, 82.

[7] Akhtar M., Young I., Brody H.: "Anterior pituitary component in benign cystic ovarian teratomas. Report of three cases". Am. J. Clin. Pathol., 1975, 64, 14.

[8] McKee! D. W. Jr, Askin F. B.: "Ectopic hypophyseal hormonal cells in benign cystic teratoma of the ovary. Light microscopic histochemical dye staining and immunoperoxidase cytochemistry" Arch. Pathol. Lab. Med., 1978, 102, 122.

[9] Flombaum C. D.: "Metabolic emergencies in the cancer patient". Semin. Oneal., 2000, 27, 322.

[10] Tomita M., Suzuki H., Matsuoka Y., Sakurada N.: "Increased renal kallikrein excretion in SIADH after vincristine therapy". Endocinol. Jpn., 1981, 28, 637.

[11] Stems R. H., Silver S. M., Spital A.: "Hyponatremia". In: Seldin D. W., Giebisch G. (eds.): "The Kidney: Physiology and Pathophysiology". Vol I., 3rd ed., Philadelphia, Lippincott Williams& Wilkins, 2000, 1217.

[12] Chow K. M., Szeto C. C.: "Hyponatraemia in a woman with a pelvic mass". Postgrad. Med. ]., 2003, 79, 61.

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