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Postmenopausal endometrial cancer screening: is there a correlation between transvaginal sonographic measurement of endometrial thickness and body mass index?
1Assist. Prof, Department of Obstetrics and Gynecology, Kahramanmaras Sutcuimam University Medical Faculty, Kahramanmaras, Turkey
2Assist. Prof,Department of Obstetrics and Gynecology, Mersin University Medical Faculty, Mersin, Turkey
3Assist. Prof, Department of Pathology, Kahramanmaras Sutcuimam University Medical Faculty, Kahramanmaras, Turkey
4Assoc. Prof, Inonu Department of Obstetrics and Gynecology, University Medical Facully,Malatya, Turkey
5Resident, Department of Obstetrics and Gynecology, Facully of Medicine, Ege University, Izmir, Turkey
*Corresponding Author(s): M.A. Giiven E-mail:
Objective: The aim of this study was to correlate the body mass index with transvaginal sonographic measurement of endometrial thickness in a cohort of postmenopausal women who were admitted for endometrial cancer surveillance.
Material and methods: Transvaginal sonographic measurement of endometrial thickness was performed in 97 postmenopausal women who attended the gynecology clinic for endometrial cancer screening with no history of hormone replacement therapy and correlated with body mass index. Baseline characteristics including age, years since menopause and body mass index were recorded for each subject. The relationship between transvaginal sonographic endometrial thickness and baseline characteristics was assessed in each.
Results: Body mass index was significantly correlated with years since menopause (r = 0.292, p = 0.004) and age (r = 0.243, p = 0.01) but not with endometrial thickness (r = -0.07, p = 0.454). Endometrial thickness versus time since menopause correlation was found to be significant (r = 0.274, p = 0.03) in patients with a body mass index lower than 30.
Conclusion: The present findings indicate that endometrial thickness does not differ with body mass index in the screening of postmenopausal women for endometrial cancer.
Transvaginal sonography; Body mass index; Endometrial thickness
M.A. Giiven,O. Pata,S. Bakaris,A. Kafkash,L. Mgoyi. Postmenopausal endometrial cancer screening: is there a correlation between transvaginal sonographic measurement of endometrial thickness and body mass index?. European Journal of Gynaecological Oncology. 2004. 25(3);373-375.
[1] Kufahl J., Pedersen I., Sindberg E.P., Helkjaer P.E., Larsen L.G., Jensen K.L.: "Transvaginal ultrasound, endometrial cytology sampled by gynoscann and histology obtained by uterine explora curette compared to the histology of the uterine specimen: a prospective study in pre- and postmenopausal women undergoing elective hsyterectomy". Acta Obstet. Gynecol. Scand., 1997, 76, 790.
[2] Gull B., Carlsson S., Karlsson B., Ylostalo P., Milsom I., Granberg S.:'Transvaginal ultrasonography of the endoemtrium in women with postmenopausal bleeding: is it always necessary to perform an endometrial biopsy7". Am. 1. Obstet. Gynecol., 2000, 182, 509.
[3] Fleischer A.C., Pittaway D.E., Beard L.A., Thieme G.A., Bundy A.L., James A.E.: "Sonographic depiction of endoemtrial changes occurring with ovulation induction". 1. Ultrasound Med., 1984, 3, 341.
[4] Nakamura Y., Ono M., Yoshida Y., Sugino N., Ueda K., Kato H.: "Effects of clomiphene citrate on the endometrial thickness and echogenic pattern of the endometrium". Fertil. Steril., 1997, 67, 256.
[5] MacDonald P.C., Edman C.D., Hemsell D.L., Porter J.C., Siiteri P.K.: "Effect of obesity on conversion of plasma androstenedione to estrone in postmenopausal women with and without endometrial cancer". Am. 1. Obstet. Gynecol., 1978, 130, 448.
[6] Meldrum D.R., Davidson B.J., Tataryn I.V., Judd H.L.: "Changes in circulating steroids with aging in postmenopausal women" Obstet. Gynecol., 1981, 628, 624.
[7] Siiteri P.K.: "Adipose tissue as a source of hormones". Am. J. Clin. Nutr., 1987, 45, 277.
[8] Warming L., Ravn P., Christiansen C.: "Visceral fat is more important than peripheral fat for endometrial thickness and bone mass in healthy postmenopausal women". Am. J. Obstet. Gynecol., 2003, 188, 349.
[9] Andolf E., Dahlander K., Aspenberg P.: "Ultrasonic thickness of the endoemtrium correlated to body weight in asymptomatic postmenopausal women". Obstet. Gynecol., 1993, 82, 936.
[10] Douchi T., Yoshinaga M., Katanozaka M., Mitani M., Nagata Y.: "Relationship between body mass index and transvaginal ultrasonographic endometrial thickness in postmenopausal women". Acta Obstet. Gynecol. Scand., 1998, 77, 905.
[11] Van den Bosch T., Vandendael A., Van Schoubroeck D., Lombard C.J., Wranz P.A.: "Age, weight, body mass index and endometrial thickness in postmenopausal women". Acta Obstet. Gynecol. Scand., 1996, 75, 181.
[12] Gull, Karlsson B., Milsom I., Granberg S.: "Factors associated with endometrial thickness and uterine size in a random sample of postmenopausal women". Am. J. Obstet. Gynecol., 2001, 185, 386.
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