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Aggressive angiomyxoma of the vagina: a case report and review of the literature
1Department of Pathology, University Hospital of Ioannina, Ioannina, Greece
2Department of Obstetrics and Gynecology, University Hospital of Ioannina, Ioannina, Greece
*Corresponding Author(s): N.J. Agnantis E-mail:
Aggressive angiomyxoma (AA) is a rare mesenchymal tumor of the lower pelvis and genital region, characterized by local infiltration and frequent, even multiple recurrences. In the present paper a case of a small-sized AA of the vagina, in a 55-year-old woman is reported. We describe the histological appearance and the immunohistochemical phenotype of this tumor and discuss its differential diagnosis from other mesenchymal lesions occurring in the pelvic and genital region. Furthermore, we attempt to enlighten the possible mechanisms that govern the pathogenesis and the biological behavior of this "mysterious" neoplasm.
Aggressive angiomyxoma; Immunohistochemistry; Behavior; Treatment; Prognosis
D.J. Papachristou,A. Batistatou,E. Paraskevaidis,N.J. Agnantis. Aggressive angiomyxoma of the vagina: a case report and review of the literature. European Journal of Gynaecological Oncology. 2004. 25(4);519-521.
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