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Cutaneous metastasis of endometrial carcinoma with hemorrhagic nodules and papules
1Inonu University, School of Medicine, Department of Internal Medicine, Division of Hematology, Turgut Ozal Medical Center, Malatya, Turkey
2Gaziantep University, Department of Internal Medicine, Division of Medical Oncology, Sahinbey Medical Center, Gaziantep, Turkey
3Inonu University, School of Medicine, Department of Pathology, Turgut Ozal Medical Center, Malatya, Turkey
*Corresponding Author(s): A. Sevinc E-mail:
Background: Endometrium cancer is the fourth most frequent malignancy in women. However, skin metastasis from endometrium cancer is a very rare entity.
Case: A 58-year-old multiparous woman postmenopausal for ten years presented with multiple metastatic, nodular, hemorrhagic skin lesions located at the initial surgery and radiotherapy site 14 months after the original diagnosis was made. Combination chemotherapy was instituted, but the patient died after the second cycle of chemotherapy.
Conclusion: Although endometrial cancer is one of the most frequent malignancies in women, skin metastasis from endometrial cancer is very rare. In reported cases metastasis from endometrial cancer has been most commonly noted at the initial surgery and radiotherapy site. Therefore, the initial surgical and radiotherapy site must be examined carefully for skin metastasis.
Endometrial carcinoma; Skin; Metastasis; Radiotherapy
M. Baydar,M. Dikilitas,A. Sevinc,S. Senel,F. Senel,I. Aydogdu. Cutaneous metastasis of endometrial carcinoma with hemorrhagic nodules and papules. European Journal of Gynaecological Oncology. 2005. 26(4);464-467.
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