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Original Research

Open Access

Incidence of endometrial carcinoma in patients with endometrial hyperplasia

  • L. Novac1,*,
  • T. Grigore1
  • N. Cernea1
  • M. Niculescu2
  • S. Cotarcea3

1Department of Obstetrics and Gynaecology, Romania

2Department of Anatomy, University of Medicine and Farmacology of Craiova, Romania

3Department of Clinical Research, Municipal Hospital of Craiova, Romania

DOI: 10.12892/ejgo200505561 Vol.26,Issue 5,September 2005 pp.561-563

Published: 10 September 2005

*Corresponding Author(s): L. Novac E-mail:

Abstract

Objective: The purpose of this retrospective study was to establish the risk of developing endometrial adenocarcinoma in patients diagnosed with endometrial hyperplasia.

Material and methods: The incidence of endometrial hyperplasia and its relation with endometrial adenocarcinoma was evaluated in 1,139 patients who presented with abnormal bleeding between January 2000 and December 2004; D&C was performed in all cases. There were 591 (51.88%) cases of simple endometrial hyperplasia, out of which 110 (18.61% from 51.88%) cases had atypia, 60 (5.26%) cases of complex hyperplasia, out of which 19 (31.66% from 5.26%) had atypia, and the remaining 488 (42.84%) had different forms of mixed hyperplasia.

Results: The incidence of endometrial adenocarcinoma was 3.87% in atypical hyperplasia and 0.81% in other forms, and was related only to cases with atypia in which the incidence was 0.61%.

Conclusions: The most indicated measure to prevent endometrial carcinoma in cases with complex endometria hyperplasia with atypia is hysterectomy, while for other forms of hyperplasia, hormonal treatment is used but only under strict control.

Keywords

Endometrial hyperplasia; Atypical hyperplasia; Endometrial carcinoma

Cite and Share

L. Novac,T. Grigore,N. Cernea,M. Niculescu,S. Cotarcea. Incidence of endometrial carcinoma in patients with endometrial hyperplasia. European Journal of Gynaecological Oncology. 2005. 26(5);561-563.

References

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