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Cervical cancer in pregnant women: Laparoscopic evaluation before delaying treatment

  • C. Stan1
  • E. Megevand1
  • O. Irion1
  • C. Wang1
  • I. Bruchim2
  • P. Petignat1,3,*,

1Gynecologic Oncology and Senology Service, University Hospitals of Geneva, Geneva, Switzerland

2Gynecologic Oncology Service, McGill University, Montreal, Canada

3Gynecologic Oncology Service, University of Montreal, Montreal, Canada

DOI: 10.12892/ejgo200506649 Vol.26,Issue 6,November 2005 pp.649-650

Published: 10 November 2005

*Corresponding Author(s): P. Petignat E-mail:

Abstract

Background: Cervical carcinoma diagnosed during pregnancy generates conflicting concerns between control of malignancy and continuation of pregnancy.

Case: An invasive cervical carcinoma FIGO Stage IB2 was diagnosed in a 33-year-old primigravida during the first trimester of pregnancy. Because the patient strongly desired to preserve her pregnancy, laparoscopic lymphadenectomy was performed at 16 weeks of gestation to determine the extension of disease. Negative lymph node status was found and the patient was counseled about the possibility of proceeding until adequate fetal maturity had been achieved. An elective cesarean section and radical hysterectomy were performed at 36 weeks, followed by postoperative chemoradiation therapy. The clinical and Pap smear follow-up remain normal after four years.

Conclusion: Pregnant women diagnosed with early stage cervical carcinoma should receive a complete evaluation including lymphadenectomy before considering delayed therapy. This strategy seems to be an acceptable option in well-defined conditions, and offers these patients the possibility of maternity.

Keywords

Cervical cancer; Laparoscopy; Pregnancy; Treatment delay

Cite and Share

C. Stan,E. Megevand,O. Irion,C. Wang,I. Bruchim,P. Petignat. Cervical cancer in pregnant women: Laparoscopic evaluation before delaying treatment. European Journal of Gynaecological Oncology. 2005. 26(6);649-650.

References

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[3] Jones W.B., Shingleton H.M., Russell A., Fremgen A.M., Chve R.E., Winchester D.P., Chmiel J.S.: "Cervical carcinoma and pregnancy. A national patterns of care study of the American College of Surgeons". Cancer, 1996, 77, 1479.

[4] Takushi M., Moromizato H., Sakumoto K., Kanazawa K.: "Management of invasive carcinoma of the uterine cervix associated with pregnancy: outcome of intentional delay in treatment". Gynecol Oncol., 2002, 87, 185.

[5] Sood A.K., Sorosky J. I., Krogman S., Anderson B., Benda J., Buller R.E.: "Surgical management of cervical cancer complicating pregnancy: a case-control study". Gynecol. Oncol., 1996, 63, 294.

[6] Nguyen C., Montz F.J., Bristow R.E.: "Management of Stage I cervical cancer in pregnancy". Obstet. Gynecol. Surv., 2000, 55, 633.

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