Article Data

  • Views 186
  • Dowloads 122

Reviews

Open Access

Sertoli cell tumor: a rare case in an elderly patient

  • M.O. Nicoletto1,*,
  • E. Caltarossa2
  • M. Donach2
  • G.B. Nardelli1
  • A. Parenti3
  • A. Ambrosini1

1Department of Medical Oncology, Padua Hospital, Padova, Italy

2Department of Gynecology of University of Padua, Italy

3Pathology Service, University of Padua, Padova, Italy

DOI: 10.12892/ejgo20060186 Vol.27,Issue 1,January 2006 pp.86-87

Published: 10 January 2006

*Corresponding Author(s): M.O. Nicoletto E-mail:

Abstract

Sertoli-Leydig cell tumors constitute < 1% of ovarian tumors, mostly in young women with virilization; however, not all present endocrine manifestations. A 72-year-old female presented with an abdominal mass and no signs of virilization. Total abdominal hysterectomy with bilateral salpingo-oophorectomy, omentectomy and selective pelvic lymphadenectomy was performed. The pathologic diagnosis was poorly-differentiated sex cord-stromal tumor with Sertoli cells. No adjuvant chemotherapy or radiation was administered. At 12-month follow-up the patient showed no evidence of disease.

Keywords

Sertoli-Leydig cell tumors; Elderly; Ovarian cancer

Cite and Share

M.O. Nicoletto,E. Caltarossa,M. Donach,G.B. Nardelli,A. Parenti,A. Ambrosini. Sertoli cell tumor: a rare case in an elderly patient. European Journal of Gynaecological Oncology. 2006. 27(1);86-87.

References

[1] Ergete W., Kiros K.: "An ovarian Sertoli-Leydig cell tumour in a 40 year old Ethiopian woman: case report". Ethiop. Med. J., 2000, 38, 185.

[2] Zaloudek C., Norris H.J.: "Sertoli-Leydig tumors of the ovary". Am. J. Pathol., 1984, 8,405.

[3] Young R.H., Scully R.E.: "Ovarian Sertoli-Leydig cell tumours". Am. J. Surg. Pathol., 1985, 9, 543.

[4] Britt K.L., Findlay J.K.: "Regulation of the phenotype of ovarian somatic cells by estrogen". Mo/. Ce/. Endocrinol., 2003, 202, 11.

[5] Young R.H.: "Sertoli-Leydig cell tumors of the ovary: Review with emphasis on historical aspects and unusual variants". Int. J. Gynecol. Pathol., 1993, 12, 141.

[6] Latthe P., Shafi M.I., Rollason T.P.: "Recurrence of Sertoli-Leydig cell tumor in controlateral ovary. Case report and review of literature". Eur. J. Gynaecol. Oneal., 2000, 21, 62.

[7] Lantzsch T., Stoerer S., Lawrenz K.: "Sertoli-Leydig cell tumor". Arch. Gynecol. Obstet., 2001, 206.

[8] Campisi P., Cheski P.: "Metastatic Sertoli-Leydig cell ovarian cancer manifested as a frontal sinus mass". J. Otolaryngol., 1998, 27, 361.

[9] Gershenson D.M., Morris M., Burke T.W.: "Treatment of poorprognosis sex cord-stromal tumors of the ovary with the combination of bleomycin, etoposide and cisplatin". Obstet. Gynecol., 1996, 87, 527.

[10] Gheorghisan-Galateanu A., Pica S., Terzea D.C.: "Sertoli-Leydig cell tumor - a rare androgen secreting ovarian tumor in postmenopausal women". J. Cell Mo/. Med., 2003, 7, 461.

[11] Appetecchia M., Cela V., Bernardi F., Burelli A., Cionini R., Pucci E.: "Sertoli-Leydig cell androgens-estrogens secreting tumor of the ovary: ultra-conservative surgery". Eur. J. Obstet. Gynecol. Reprod. Biol., 2004, 116, 113.

[12] Lara-Torre E., Dietrich J.E., Kaplan A., Lopez H., Jaffee I.: "A case of poorly differentiated Sertoli-Leydig tumor of the ovary". J Pediatr. Adolesc. Gynecol., 2004, 17, 49.

[13] Tampakoudis P., Zafrakas M., Kostopoulou E.: "Ovarian SertoliLeydig cell tumor with coexisting vaginal angiomyxoma: case report and review of the literature". Eur. J. Gynecol. Oncol., 2004, 25, 116.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top