Article Data

  • Views 196
  • Dowloads 120

Case Reports

Open Access

Double laparotomy wound recurrence of endometrial carcinoma

  • G.C. Balbi1,*,
  • A. Cardone1
  • A. Monteverde1
  • M. Passaro1
  • L. Montone1
  • R. Rossiello1
  • S. Visconti1
  • M. Battisti1
  • E. Cassese1
  • I. Landino1

1Department of Obstetrics and Gynecology, Department of Pathological Anatomy, "L. Armanni" Second University of Naples (SUN), Naples, Italy

DOI: 10.12892/ejgo200603307 Vol.27,Issue 3,May 2006 pp.307-309

Published: 10 May 2006

*Corresponding Author(s): G.C. Balbi E-mail:

Abstract

Introduction: Abdominal scar recurrence of endometrial carcinoma after abdominal total hysterectomy is very rare. We report a case of a 65-year-old woman who had two recurrences in the abdominal incisional scar after total hysterectomy.

Case report: A 65-year-old woman underwent total hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy because of well-differentiated endometrial adenocarcinoma (Stage IIB). Thus, the patient was treated by external beam radiotherapy. She developed two recurrences in the abdominal incisional scar two and three years after total hysterectomy, respectively. Surgery plus chemotherapy and surgery plus hormonal therapy were used for treatment of the first and second scar recurrence, respectively.

Conclusions: It is a very intriguing and controversial biologic question how neoplastic cells can implant and grow in an abdominal scar without other concomitant metastases. We report a review of the literature and the possible mechanism of recurrences in laparotomy wounds.

Keywords

Endometrial cancer; Recurrence; Survival of recurring patients

Cite and Share

G.C. Balbi,A. Cardone,A. Monteverde,M. Passaro,L. Montone,R. Rossiello,S. Visconti,M. Battisti,E. Cassese,I. Landino. Double laparotomy wound recurrence of endometrial carcinoma. European Journal of Gynaecological Oncology. 2006. 27(3);307-309.

References

[1] Wahlgvist L.: "Resection of the abdominal wall in metastasis from cancer of bladder, kidney or colon". Eur. Ural., 1977, 3, 26.

[2] Bedwinek J., Galakotos A. et al.: "Stage I grade III, adenocarc1-noma of the endometrium treated with surgery and irradiation". Cancer, 1984, 54, 40.

[3] Chambers S.K., Kapp D.S. et al.: "Prognostic factors and sites of failure in FIGO stage I, grade III, endometrial carcinoma". Gynecol. Oneal., 1987, 27, 180.

[4] Curtis M.G., Hopkins M.P. et al.: "Wound seeding associated with endometrial cancer". Gynecol. Oncol., 1994, 52, 413.

[5] Espinos J., Garcia-Patos V. et al.: "Early skin metastasis of endometrial carcinoma: case repost and review of literature" Cutis, 1993, 52, 109.

[6] Khalil Am., Chammes M.F. et al.: "Case report; endometrial cancer implanting in the laparotomy scar". Eur. J. Gynecol Oncol., 1998, 19, 408.

[7] Kotwall C.A., Kirkbride P. et al.: "Endometrial cancer and abdominal wound recurrence". Gynecol Oncol., 1994, 53, 357.

[8] Joshi S.C., Sharma D.N. et al.: "Endometrial carcinoma with recurrence in the incisional scar: A case report". Int. J. Gynecol. Cancer, 2003, 13, 901.

[9] Lorenz U., Gassel A.M. et al.: "Endometrial carcmoma recurrence in an abdominal scar 14 years after total hysterectomy". Gynecol. Oncol., 2004, 95, 393.

[10] Macias V., Baiotto B. et al.: "Laparotomy wound recurrence of endometrial cancer". Gynecol. Oncol., 2003, 91, 429.

[11] Muntz H.G., Goff B.A. et al.: "Port-site recurrence after laparoscopic surgery for endometrial carcinoma". Obstet. Gynecol., 1999, 93, 807.

[12] Ramirez P.T., Frumovitz M. et al.: "Laparoscopic port-site metastases in patients with gynaecological malignancies". Int. J Gynecol. Cancer, 2004, 14, 1070.

[13] Chapman G.W., Fabacher P.: "lncisional recurrence of endometrial carcinoma". J. Nat. Med. Assoc., 1988, 80, 359.

[14] American Cancer Society (ACS): Cancer facts and figures Atlanta, 1998. G.A.: ACS, 1998.

[15] Sonoda Y.: "Optimal therapy and management of endometrial cancer". Expert Rev. Anticancer Ther, 2003, 3, 37.

[16] Sutton G.P.: "The significance of positive peritoneal cytology in endometrial cancer". Oncology, 1990, 4, 23.

[17] Ardies C.M.: "Inflammation as cause for scar cancers of the lung" Integr. Cancer Ther., 2003, 2, 238.

[18] DerHagopian R.P., Sugerbaker E.V.: "Inflammatory oncotaxis" JAMA, 1978, 240, 374.

[19] Morrow C., Bundy B. et al.: "Relationships between surgicalpathologic risk factors and outcome in clinical stage I and II carcinoma of the endometrium: A Gynecologic Oncology Group study". Gynecol. Oncol., 1991, 40, 55.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top