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Fulminant course of metastatic liposarcoma after delivery -case report

  • L Rousková1
  • B. Melichar2,3,*,
  • D.H. Nikolov4
  • J. Cerman Jr.5
  • E Havel6
  • J Megancová6
  • H Urminská7
  • P Jandík6

1Departments of Obstetrics & Gynecology, Charles University Medical School & Teaching Hospital, Hradec Krdlove, Czech Republic

2Departments of Oncology & Radiotherapy, Charles University Medical School & Teaching Hospital, Hradec Krdlove, Czech Republic

3Departments of Medicine, Charles University Medical School & Teaching Hospital, Hradec Krdlove, Czech Republic

4Departments of Pathology, Charles University Medical School & Teaching Hospital, Hradec Krdlove, Czech Republic

5 Departments of Hematology, Charles University Medical School & Teaching Hospital, Hradec Krdlove, Czech Republic

6Departments of Surgery, Charles University Medical School & Teaching Hospital, Hradec Krdlove, Czech Republic

7Departments of Radiology, Charles University Medical School & Teaching Hospital, Hradec Krdlove, Czech Republic

DOI: 10.12892/ejgo20070167 Vol.28,Issue 1,January 2007 pp.67-68

Published: 10 January 2007

*Corresponding Author(s): B. Melichar E-mail:

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Abstract

Abdominal liposarcoma is a rare tumor of uncertain prognosis. Radical surgery is possible in about two-thirds of the patients, and the prognosis of patients with inoperable tumors is dismal. Only a few cases of liposarcoma complicating pregnancy have been documented. We report a case of a patient who was diagnosed with metastatic abdominal liposarcoma during the third trimester of the pregnancy. After induced vaginal delivery, palliative surgery was performed and one cycle of systemic combination chemotherapy was administered. Despite the multimodality treatment the patient died of progressive disease within one month after diagnosis. Autopsy revealed high-grade pleomorphic liposarcoma arising from the retroperitoneum with liver and lung metastases.

Keywords

Liposarcoma; Pregnancy; Retroperitoneum

Cite and Share

L Rousková,B. Melichar,D.H. Nikolov,J. Cerman Jr.,E Havel,J Megancová,H Urminská,P Jandík. Fulminant course of metastatic liposarcoma after delivery -case report. European Journal of Gynaecological Oncology. 2007. 28(1);67-68.

URL:

https://www.ejgo.net/articles/10.12892/ejgo20070167

References

[1] Jaques D.P., Coit D.G., Hajdu S.I., Brennan M.F.: "Management of primary and recurrent soft-tissue sarcoma of the retroperitoneum" Ann. Surg., 1990, 212, 51.

[2] Yamamoto T., Marui T., Akisue T., Hitora T., Kawamoto T., Nagira K. et al.: "Management of liposarcoma occurring in pregnant women". Anticancer Res., 2003, 23, 799.

[3] Frank P., Batzenschlager A., Schaeffer F., Irrmann M.: "Problemes thréapeutiques poses par Jes liposarcomes intra-abdominaux" Chirurgie 1989,JJ5, 446.

[4] Tebes S., Cardosi R., Hoffman M.: "Liposarcoma complicatmg pregnancy". Gynecol. Oncol., 2001, 83,610.

[5] De Jaco P., Giorgio M., Zantedeschi B., Mazzoleni G., Marabini A "A case of retroperitoneal liposarcoma in pregnancy". Acta Obste Gynecol. Scand., 1993, 72, 122.

[6] Khelifati Y., Abd-Alsamad I., Haddad B., Touboul C., Scherer A., Paniel B.J.: "Liposarcome myxoide pelvien. A propos d'un cas". J Gynecol. Obstet. Biol. Reprod., 1995, 24, 264. [7] Foruhan B.: "Retroperitoneal sarcomas obstructing delivery. Two case reports". 81: J. Obstet. Gynaecol., 1979, 86, 9.

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