Diabetes mellitus is a multivariate independent prognostic factor in endometrial carcinoma: A clinicopathologic study on 313 patients

Objective: The aim of this study was to analyse the influence of diabetes mellitns as a prognostic factor for overall survival in endometrial cancer. Materials and Methods: Charts were reviewed from patients with endometrial carcinoma from 1985 to 2003. Data on clinicopathologic variables, adjuvant treatment, site of recurrence and survival were collected. The chi-square test was nsed to examine associations between variables. The Kaplan-Meier method was used for survival analysis and Cox's proportional hazards model for multiple regression analysis. Results: Multivariate analysis revealed that diabetes mellitus, FIGO stage and depth of myometrial invasion were significantly associated with overall survival.

Endometrial cancer: Diabetes mellitus; Prognostic factor: Overall survival

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