Can “chromohysteroscopy” help target endometrial biopsy in postmenopausal bleeding ?

A preliminary study was conducted to evaluate the value of endometrial dying during diagnostic hysteroscopy. Twenty-two postmenopausal bleeding cases without hysteroscopic findings were included in the study. Before the random endometrial biopsy 5 ml of methylene blue (1%) was instilled into the uterine cavity. Staining was observed in 19 of the cases. Tissues were obtained from both stained and non-stained areas with grasping forceps. "Chromohysteroscopy" led the diagnosis of three more endometrial pathologies; two more cases of endometritis and one more case of endometrial hyperplasia. In conclusion, chromohysteroscopy seems like a new avenue worth pursuing for better diagnoses of unexplained endometrial pathologies.

Postmenopausal bleeding; Hysteroscopy; Chromohysteroscopy; Methylene blue

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