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A sarcomatous-type peritoneal malign mixed mullerian tumor implant in association with ovarian adenocarcinoma: a case report
1Department of Obstetrics and Gynecology, Gulhane Military Medical Academy, Ankara, Turkey
*Corresponding Author(s): K. Gezginç E-mail:
A rare case of a patient with a histopathological diagnosis of a sarcomatous-type peritoneal malign mixed mullerian tumor implant in association with ovarian adenocarcinoma is reported. A 52-year-old patient was referred to our clinic for an adnexal mass. At pelvic examination, an irregular, fixed, approximately 7-8 cm in size mass was detected in the right adnexal area. At transvaginal ultrasonographic examination, it was observed that there was an 80 x 70 mm sized, irregularly contoured, semisolid mass with hyper-echogenous areas inside originating from the ovary in the right adnexal area. At laboratory examination tumor marker CA-125 was 280.4 U/ml (< 35), CA-15-3 was 146.5 U/ml (< 25), whereas other markers were within normal range. The patient was operated on for a right adnexal mass. A staging laparatomy procedure was applied. Postoperative histopathological diagnosis was reported as malignant mixed mullerian tumor of the ovary, with the ovarian component as poorly differentiated adenocarcinoma, and the metastatic foci over serosal surfaces as a sarcomatous component. Postoperatively six courses of adjuvant and consolidation chemotherapy were administered to the patient. Further studies are needed to set a consensus about evaluation of treatment and prognosis for this kind of pathology.
Ovarian malign mixed mullerian tumor; Peritoneal implant; Treatment
M. Dede,K. Gezginç,I·. Alanbay,U. Fidan,M. Yenen. A sarcomatous-type peritoneal malign mixed mullerian tumor implant in association with ovarian adenocarcinoma: a case report. European Journal of Gynaecological Oncology. 2008. 29(2);193-195.
[1] Wei L.H., Huang C.Y., Cheng S.P., Chen C.A., Hsieh C.Y.: “Carcinosarcoma of ovary associated with previous radiotherapy”. Int. J. Gynecol. Cancer, 2001, 11, 81.
[2] Ariyoshi K., Kawauchi S., Kaku T., Nakano H., Tsuneyoshi M.: “Prognostic factors in ovarian carcinosarcoma: a clinicopathological and immunohistochemical analysis of 23 cases”. Histopathology, 2000, 37, 427.
[3] Muntz H.G., Jones M.A., Goff B.A. et al.: “Malignant mixed mullerian tumors of the ovary: experience with surgical cytoreduction and combination chemotherapy”. Cancer, 1995, 76, 1209.
[4] Bicher A., Levenback C., Silva E.G., Burke T.W., Morris M., Gershenson D.M.: “Ovarian malignant mixed mullerian tumors treated with platinum- based chemotherapy”. Obstet. Gynecol., 1995, 85, 735.
[5] Gallardo A., Matias-Guiu X., Lagarda H. et al.: “Malignant mullerian mixed tumor arising from ovarian serous carcinoma: a clinicopathologic and molecular study of two cases”. Int. J. Gynecol. Pathol., 2002, 21, 268.
[6] Scully R.E., Young R.H., Clement P.B.: “Tumors of the ovary, maldeveloped gonads, fallopian tube, and broad ligament”. In: Rosai J. (ed.). Atlas of Tumor Pathology, 3rd series, fascicle 23 Washington, DC: Armed Forces Institute of Pathology, 1998, 128.
[7] Hellstrom A.C., Tegerstedt G., Silfversward C., Pettersson F.: “Malignant mixed mullerian tumors of the ovary: histopathologic and clinical review of 36 cases”. Int. J. Gynecol. Cancer, 1999, 9, 312.
[8] Bicher A., Levenback C., Silva EG., Burke T.W., Morris M., Gershenson D.M.: “Ovarian malignant mixed mullerian tumors treated with platinum-based chemotherapy”. Obstet. Gynecol. 1995, 85, 735.
[9] Baker TR., Piver MS., Caglar H., Piedmonte M.: “Prospective trial of cisplatin, adriamycin, and dacarbazine in metastatic mixed mesodermal sarcomas of the uterus and ovary”. Am. J. Clin. Oncol., 1991, 9, 246.
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