Article Data

  • Views 235
  • Dowloads 100

Original Research

Open Access

Metastatic spread of gynaecological neoplasms to the adrenal gland: case reports with a review of the literature

  • M. Baron1,*,
  • L. Hamou1
  • S. Laberge2
  • F. Callonnec3
  • A. Tielmans4
  • P. Dessogne1

1Department of Surgery, France

2Department of Pathology, France

3Department of Radiology, Becquerel Cancer Center, France

4Department of Endocrinology, Rouen University Hospital, Rouen, France

DOI: 10.12892/ejgo200805523 Vol.29,Issue 5,September 2008 pp.523-526

Published: 10 September 2008

*Corresponding Author(s): M. Baron E-mail: marc.baron@rouen.fnclcc.fr

Abstract

Metastatic involvement of the adrenal glands due to gynaecological neoplasms is a relatively rare condition. The aim of our Study was to present four cases of metastases to the adrenal gland due to endometrial adenocarcinoma, ovarian and cervical cancer. These cases are correlated with a review of the literature. CT scan and MRI have been previously used in an attempt to define the nature of the adrenal mass but this approach is of limited value in diagnosis. Image-guided pathological confirmation of an adrenal lesion may significantly change the staging or management of the primary neoplasm. The authors suggest that isolated adrenal metastasis should be routinely considered for surgical management.

Keywords

Adrenal metastasis; Endometrial adenocarcinoma; Ovarian cancer; Cervical cancer; Vulvar cancer

Cite and Share

M. Baron,L. Hamou,S. Laberge,F. Callonnec,A. Tielmans,P. Dessogne. Metastatic spread of gynaecological neoplasms to the adrenal gland: case reports with a review of the literature. European Journal of Gynaecological Oncology. 2008. 29(5);523-526.

References

[1] Kim S.H., Brennan M.F., Russo P., Burt M.E., Coit D.G.: “The role of surgery in the treatment of clinically isolated adrenal metastasis”. Cancer, 1998, 82, 389.

[2] Abrams H.L., Spiro R., Goldstein N.: “Metastases in carcinoma: analysis of 1000 autopsied cases”. Cancer, 1950, 3, 74.

[3] Gross B.H., Goldberg H.I., Moss A.A., Harter L.P.: “CT demonstration and guided aspiration of unusual adrenal metastasis”. J. Computer Assist. Tomograp., 1983, 7, 98.

[4] Katz R.L., Shirkhoda A.: “Diagnostic approach to incidental adrenal nodules in the cancer patient. Results of a clinical, radiologic and fine-needle aspiration study”. Cancer, 1985, 55, 1995.

[5] Seidenwurm D.J., Elmer E.B., Kaplan L.M., Williams E.K., Morris D.G., Hoffman A.R.: “Metastases to the adrenal glands and the development of Addison’s disease”. Cancer, 1984, 54, 552.

[6] Yun M., Kim W., Alnafisi N., Lacorte L., Jang S., Alavi A.: “18FFDG PET in characterizing adrenal lesions detected on CT or MRI”. J. Nucl. Med., 2001, 12, 1795.

[7] Welch T.J., Sheedy P.F., Stephens D.H., Johnson C.M., Swensen S.J.: “Percutaneous adrenal biopsy: review of a 10-year experience”. Radiology, 1994, 193, 341.

[8] Sarela A.I., Murphy I., Coit D.G., Conlon K.C.: “Metastasis to the adrenal gland: the emerging role of laparoscopic surgery”. Ann. Surg. Oncol., 2003, 10, 1191.

[9] Drescher C.W., Hopkins M.P., Roberts J.A.: “Comparison of the pattern of metastatic spread of squamous cell cancer and adenocarcinoma of the uterine cervix”. Gynecol. Oncol., 1989, 33, 340.

[10] Dvoretsky P.M., Richards K.A., Angel C., Rabinowitz L., Stoler M.H., Beecham J.B. et al.: “Distribution of disease at autopsy in 100 women with ovarian cancer”. Hum. Pathol., 1988, 19, 57.

[11] Einat S., Amir D., Silvia M., Moshe I.: “Successful laparoscopic removal of a solitary adrenal metastasis from ovarian carcinoma : a case report”. Gynecol. Oncol., 2002, 85, 201.

[12] Patlas M., O’Malley M.E., Chapman W.: “Adrenal metastasis from ovarian carcinoma”. AJR Am. J. Roentgenol., 2004, 183, 1711.

[13] Redman B.G., Pazdur R., Zingas A.P., Loredo R.: “Prospective evaluation of adrenal insufficiency in patients with adrenal metastasis”. Cancer, 1987, 60, 103.

[14] Nakano K.K., Schoene W.C.: “Endometrial carcinoma with a predominant clear-cell pattern with metastases to the adrenal, posterior mediastinum, and brain”. Am. J. Obstet. Gynecol., 1975, 122, 529.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top