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Original Research

Open Access

A 15-year report of pathological and benign ovarian tumors in teenagers

  • P. Tsikouras1,*,
  • V. Liberis1
  • G. Galazios1
  • C. Panagiotidou1
  • A. Savidis1
  • A. Chatzimachail2
  • G. Maroulis1

1Department of Obstetrics and Gynecology, Greece

2Department of Pediatrics, Democritus University of Thrace, Alexandroupolis, Greece

DOI: 10.12892/ejgo200806602 Vol.29,Issue 6,November 2008 pp.602-607

Published: 10 November 2008

*Corresponding Author(s): P. Tsikouras E-mail: ptsikour@med.duth.gr

Abstract

The purpose of this retrospective Study was to determine the frequency, Clinical aspects and surgical management of ovarian masses in 52 adolescent patients, in whom surgery was deemed necessary, from 1991-2006. We considered age, symptoms, ultrasound investigations. CA 125 levels. family history. operative treatment, surgical complications tumor size, histopathological examinations, pregnancy rate and follow-tip. Ovarian lesions in teenagers include a broad array of pathologic diagnoses that have variable and non-specific presenting symptoms. The most common presenting complaint was abdominal pain in 34 (65.4%). Forty-seven patients (90.4%) had benign lesions, two (3.8%) had borderline tumors and three patients had malignant lesions (5.8%). Most of the patients who wanted to conceive Subsequently did so. For benign ovarian disorders the Operation Should be designed to optimize future fertility while in patients with malignancy, complete staging and resection of the lesion should be the first concern.

Keywords

Adolescence; Ovarian tumours; Borderline ovarian tumours; Ovarian carcinoma; Surgical treatment

Cite and Share

P. Tsikouras,V. Liberis,G. Galazios,C. Panagiotidou,A. Savidis,A. Chatzimachail,G. Maroulis. A 15-year report of pathological and benign ovarian tumors in teenagers. European Journal of Gynaecological Oncology. 2008. 29(6);602-607.

References

[1] Leibman A., Kruse B., McSweeney M.B.: “Transvaginal sonography: comparison with transabdominal sonography in the diagnosis of pelvic masses”. AJR Am. J. Roentgenol., 1988, 151, 89.

[2] King D.R.: “Ovarian cysts and tumors”. In: Welch K.J., Randolph J.G., Ravitch M.M. et al. (eds.). Pediatric Surgery. Chicago, IL, Year Book, 1986, 1341.

[3] Cass D.L., Hawkins E., Brandt M.L., Chintagumpala M., Bloss R.S., Milewicz A.L. et al.: “Surgery for ovarian masses in infants, children, and adolescents: 102 consecutive patients treated in a 15-year period”. J. Pediatr. Surg., 2001, 36, 693.

[4] Schultz K.A.P., Sencer S.F., Messinger Y., Neglia J.P., Steiner M.E.: “Pediatric ovarian tumors: a review of 67 cases”. Pediatr. Blood Cancer, 2005, 44, 167.

[5] Deligeoroglou E., Eleftheriades M., Shiadoes V., Botsis D., Hasiakos D., Kontoravdis A., Creatsas G.: “Ovarian masses during adolescence: clinical, ultrasonographic and pathologic findings, serum tumor markers and endocrinological profile”. Gynecol. Endocrinol., 2004, 19, 1.

[6] Powell J.K.: “Benign adnexal masses in the adolescent”. Adolesc. Med. Clin., 2004, 15, 535.

[7] Templeman C.L., Fallat M.E.: “Benign ovarian masses”. Semin. Pediatr. Surg., 2005, 14, 93.

[8] Lardy H., Robert M.: “Ovarian cysts assumed benign in the peripubertal period (10 to 16 years)”. J. Gynecol. Obstet. Biol. Reprod. (Paris), 2001, 30 (suppl. 1), S94.

[9] Wilczyn´qski J.R., Nowin´ska A., Szpakowski M., Nowak M., Szpakowski A., Wladzin´ski J. et al.: “Laparoscopic treatment of benign ovarian tumors”. Ginekol. Pol., 2006, 77, 40.

[10] Imai A., Furui T., Tamaya T.: “Gynecologic tumors and symptoms in childhood and adolescence; 10-years’ experience”. Int. J. Gynecol. Obstet., 1994, I 221.

[11] Templeman C.L., Hertweck S.P., Scheetz J.P., Perlman S.E., Fallat M.E.: “The management of mature cystic teratomas in children and adolescents: a retrospective analysis”. Hum. Reprod., 2000, 15, 2669.

[12] Templeman C., Fallat M.E., Blinchevsky A., Hertweck S.P.: “Noninflammatory ovarian masses in girls and young women”. Obstet. Gynecol., 2000, 96, 229.

[13] van Winter J.T., Simmons P.S., Podratz K.C.: “Surgically treated adnexal masses in infancy, childhood, and adolescence”. Am. J. Obstet. Gynecol., 1994, 170, 1780; discussion 1786.

[14] de Silva K.S., Kanumakala S., Grover S.R., Chow C.W., Warne G.L.: “Ovarian lesions in children and adolescents: an 11-year review”. J. Pediatr. Endocrinol. Metab., 2004, 17, 951.

[15] Skiadas V.T., Koutoulidis V., Eleytheriades M., Gouliamos A., Moulopoulos L.A., Deligeoroglou E. et al.: “Ovarian masses in young adolescents: imaging findings with surgical confirmation”. Eur. J. Gynaecol. Oncol., 2004, 25, 201.

[16] Sait K., Simpson C.: “Ovarian teratoma diagnosis and management: case presentations”. J. Obstet. Gynaecol. Can., 2004, 26, 137.

[17] Brown M.F., Hebra A., McGeehin K., Ross A.J. 3rd: “Ovarian masses in children: a review of 91 cases of malignant and benign masses”. J. Pediatr. Surg., 1993, 28, 930.

[18] Major T., Borsos A., Lampé L., Juhász B.: “Ovarian malignancies in childhood and adolescence”. Eur. J. Obstet. Gynecol. Reprod. Biol., 1995, 63, 65.

[19] Hanprasertpong J., Chandeying V.: “Gynecologic tumors during childhood and adolescence”. J. Med. Assoc. Thai, 2006, 89 (suppl. 4), S192.

[20] You W., Dainty L.A., Rose G.S., Krivak T., McHale M.T., Olsen C.H., Elkas J.C.: “Gynecologic malignancies in women aged less than 25 years”. Obstet. Gynecol., 2005, 105, 1405.

[21] Quero-Hernández A., Estrada-Correa R., Tenorio-Rodríguez H., Alvarez-Solís R.M.: “Malignant germ cell ovarian tumors: clinical characteristics, treatment and outcome”. Cir. Cir., 2007, 75, 81.

[22] Billmire D., Vinocur C., Rescorla F., Cushing B., London W., Schlatter M. et al.: “Outcome and staging evaluation in malignant germ cell tumors of the ovary in children and adolescents: an intergroup study”. J. Pediatr. Surg., 2004, 39, 424; discussion 424.

[23] Fotiou S.K.: “Ovarian malignancies in adolescence (review)”. Ann. N.Y. Acad. Sci., 1997, 816, 338.

[24] Menczer J., Sadetzki S., Murad H., Barda G., Andreev H., Barchana M.: “Childhood and adolescent ovarian malignant tumors in Israel. A nationwide study”. Acta Obstet. Gynecol. Scand., 1999, 78, 813.

[25] Hassan E., Creatsas G., Deligeorolgou E., Michalas S.: “Ovarian tumors during childhood and adolescence. A clinicopathological study”. Eur. J. Gynaecol. Oncol., 1999, 20, 124.

[26] Pomeranz A.J., Sabnis S.: “Misdiagnoses of ovarian masses in children and adolescents”. Pediatr. Emerg. Care, 2004, 20, 172.

[27] Mordehai J., Mares A.J., Barki Y., Finaly R., Meizner I.: “Torsion of uterine adnexa in neonates and children: a report of 20 cases”. J. Pediatr. Surg., 1991, 26, 1195.

[28] Cohen Z., Shinbar D., Kopernik G., Mares A.J.: “The laparoscopic approach to uterine adnexal torsion in childhood”. J. Pediatr. Surg., 1996, 31, 1557.

[29] Thind C.R., Carty H.M., Pilling D.W.: “The role of ultrasound in the management of ovarian masses in children”. Clin. Radiol., 1989, 40, 180.

[30] Nour S., MacKinnon A.E., Dickson J.A.: “Ovarian cysts and tumors in childhood”. J. R. Coll. Surg. Edinb., 1992, 37, 39.

[31] Wu A., Siegel M.J.: “Sonography of pelvic masses in children: diagnostic predictability”. AJR Am. J. Roentgenol., 1987, 148, 1199.

[32] Quint E.H., Smith Y.R.: “Ovarian surgery in premenarchal girls”. J. Pediatr. Adolesc. Gynecol., 1999, 12, 27.

[33] Propst A.M., Laufer M.R.: “Endometriosis in adolescents. Incidence, diagnosis and treatment”. J. Reprod. Med., 1999, 44, 751.

[34] Laufer M.R., Goitein L., Bush M., Cramer D.W., Emans S.J.: “Prevalence of endometriosis in adolescent girls with chronic pelvic pain not responding to conventional therapy”. J. Pediatr. Adolesc. Gynecol., 1997, 10, 199.

[35] Wilczyn´qski J.R., Nowin´ska A., Szpakowski M., Nowak M., Szpakowski A., Wladzin´ski J. et al.: “Laparoscopic treatment of benign ovarian tumors”. Ginekol. Pol., 2006, 77, 40.

[36] Bourdel N., Matsusakï S., Roman H., Lenglet Y., Botchorischvili R., Mage G., Canis M.: “Endometriosis in teenagers”. Gynecol. Obstet. Fertil., 2006, 34, 727.

[37] Savelli L., Ghi T., De Iaco P., Ceccaroni M., Venturoli S., Cacciatore B.: “Paraovarian/paratubal cysts: comparison of transvaginal sonographic and pathological findings to establish diagnostic criteria”. JSLS Ultrasound Obstet. Gynecol., 2006, 28, 330.

[38] Darwish A.M., Amin A.F., Mohammad S.A.: “Laparoscopic management of paratubal and paraovarian cysts”. 2003, 7, 101.

[39] Stein A.L., Koonings P.P., Schlaerth J.B., Grimes D.A., d’Ablaing G. 3rd: “Relative frequency of malignant parovarian tumors: should parovarian tumors be aspirated?”. Obstet. Gynecol., 1990, 75, 1029.

[40] Chudecka-Glaz A., Menkiszak J., Rzepka-Górska I.: “Parovarian cysts-not always benign”. Ginekol. Pol., 2002, 73, 1078.

[41] Takeda A., Manabe S., Hosono S., Nakamura H.: “Laparoscopic surgery in 12 cases of adnexal disease occurring in girls aged 15 years or younger”. J. Minim. Invasive Gynecol., 2005, 12, 234.

[42] Leiserowitz D.M., Ellenbogen A., Jaschevatzky O.E., Grünstein S.: “Fertility following adnexal surgery”. Acta Eur. Fertil., 1977, 8, 239.

[43] Canis M., Bassil S., Wattiez A., Pouly J.L., Manhes H., Mage G., Bruhat M.A.: “Fertility following laparoscopic management of benign adnexal cysts”. Hum. Reprod., 1992, 7, 529.

[44] Morice P., Camatte S., El Hassan J., Pautier P., Duvillard P., Castaigne D.: “Clinical outcomes and fertility after conservative treatment of ovarian borderline tumors”. Fertil. Steril., 2001, 75, 92.

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