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Original Research

Open Access

High levels of xenoestrogens in patients with low-grade endometrial stromal sarcoma - report of two cases

  • O. Reich1,*,
  • S. Regauer2
  • S. Scharf3

1Departments of 1Obstetrics and Gynecology , Austria

2Institute of Pathology, Medical University of Graz, Austria

3,Austria

4Institute of Pathology, Medical University of mweltbundesamt Vienna , Austria

Academic Editor: O. Reich

DOI: 10.12892/ejgo201001105 Vol.31,Issue 1,January 2010 pp.105-106

Published: 10 January 2010

*Corresponding Author(s): O. Reich E-mail: olaf.reich@meduni-graz.at

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Abstract

Background: Endometrial stromal sarcomas (ESS) are rare uterine tumors with unknown etiological risk factors, but estrogedependent growth promotion. Cases: We present two patients with advanced ESS, who had increased levels of p,p-DDE; hexachlorobenzene; PCB 28; PCB 52; PCB 101; PCB 138; PCB 153 and PCB 180 in abdominal adipose tissue. Other xenoestrogens were within expected limits for the non-exposed European population. Conclusion: Increased levels of xenoestrogens in patients with ESS may be involved in the pathogenesis of ESS. Chronic exposure to xenoestrogens may be a risk factor for tumor progression.

Keywords

Endometrial stromal sarcoma; Estrogen; Xenoestrogen; Pathogenesis.

Cite and Share

O. Reich,S. Regauer,S. Scharf. High levels of xenoestrogens in patients with low-grade endometrial stromal sarcoma - report of two cases. European Journal of Gynaecological Oncology. 2010. 31(1);105-106.

URL:

https://www.ejgo.net/articles/10.12892/ejgo201001105

References

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