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Original Research

Open Access

Prolonged survival after episiotomy recurrence of cervical cancer complicating pregnancy

  • I. Hafeez1
  • B.D. Lawenda1
  • J.M. Schilder2
  • P.A.S. Johnstone1,*,

1Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202 USA

2Division of Gynecologic Oncology, Indiana University School of Medicine, Indianapolis, IN 46202 USA

DOI: 10.12892/ejgo201102211 Vol.32,Issue 2,March 2011 pp.211-213

Published: 10 March 2011

*Corresponding Author(s): P.A.S. Johnstone E-mail: pajohnst@iupui.edu

Abstract

Background: We report a case of recurrent cervical cancer in an episiotomy scar and the late treatment-related sequelae. Case: Cervical cancer was diagnosed following a vaginal delivery, and was treated with surgery and radiotherapy. The patient developed a recurrence in her episiotomy scar, and was treated with chemoradiation. She remains without evidence of disease ten years later. Conclusion: Successful treatment of recurrent cervical cancer with chemoradiation is possible, but may be associated with significant normal tissue toxicity.

Keywords

Episiotomy; Cervical cancer; Pregnancy complication; Surgery; Radiation therapy

Cite and Share

I. Hafeez,B.D. Lawenda,J.M. Schilder,P.A.S. Johnstone. Prolonged survival after episiotomy recurrence of cervical cancer complicating pregnancy. European Journal of Gynaecological Oncology. 2011. 32(2);211-213.

References

[1] Wingo P.A., Tong T, Bolden S.: “Cancer statistics”. CA Cancer J. Clin., 1995, 45, 8.

[2] Duggan B., Muderspach L.I., Roman L.D., Curtin J.P., d’Alaing G. 3rd, Morrow C.P.: “Cervical cancer in pregnancy: reporting on planned delay in therapy”. Obstet. Gynecol., 1993, 82, 598.

[3] Burgess S.P., Waymont B.: “Implantation of a cervical carcinoma in an episiotomy site. Case report”. Br. J. Obstet. Gynaecol., 1987, 94, 598.

[4] Copeland L.J., Saul P.B., Sneige N.: “Cervical adenocarcinoma: tumor implantation in the episiotomy sites of two patients”. Gynecol. Oncol., 1987, 28, 230.

[5] Gordon A.N., Jensen R., Jones H.W. 3rd: “Squamous carcinoma of the cervix complicating pregnancy: recurrence in episiotomy after vaginal delivery”. Obstet. Gynecol., 1989, 73, 850.

[6] Van Dam P.A., Irvine L., Lowe D.G., Fisher C., Barton D.P., Shepherd J.H.: “Carcinoma in episiotomy scars”. Gynecol. Oncol., 1992, 44, 96.

[7] Khalil A.M., Khatib R.A., Mufarrij A.A., Tawil A.N., Issa P.Y.: “Squamous cell carcinoma of the cervix implanting in the episiotomy site”. Gynecol. Oncol., 1993, 51, 408.

[8] Cliby W.A., Dodson M.K., Podratz K.C.: “Cervical cancer complicated by pregnancy: episiotomy site recurrences following vaginal delivery”. Obstet. Gynecol., 1994, 84, 179.

[9] Van den Broek N.R., Lopez A.D., Ansink A., Monaghan J.M.: “‘Microinvasive’ adenocarcinoma of the cervix implanting in anepisiotomy scar”. Gynecol. Oncol., 1995, 59, 297.

[10] Goldman N.A., Goldberg G.I.: “Late recurrence of squamous cell cervical cancer in an episiotomy site after vaginal delivery”. Obstet. Gynecol., 1003, 101, 1127.

[11] Amanie J., Pearcey R.G., Honore L., Sloboda R.: “Metastatic adenocarcinoma of the cervix ina delivery-induced traumatic lower vaginal tear”. Gynecol. Oncol., 2005, 96, 857.

[12] Heron D.E., Axtel A., Gerszten K.: “Villoglandular adenocarcinoma of the cervix recurrent in an episiotomy scar: a case report in a 32- year-old female”. Int. J. Gynecol. Cancer, 2005, 15, 366.

[13] Baloglu A., Uysal D., Aslan N., Yigit S.: “Advanced stage of cervical carcinoma undiagnosed during antenatal period in termpregnancy and concomitant metastasis on episiotomy scar during delivery: a case report and review of the literature”. Int. J. Gynecol. Cancer, 2007, 17, 1155.

[14] Neumann G., Rasmussen K.L., Petersen L.K.: “Cervical adenosquamous carcinoma: tumor implantation in an episiotomy scar”. Obstet. Gynecol., 2007, 110, 467.

[15] Williams T.J., Brack C.B.: “Carcinoma of the cervix in pregnancy”. Cancer, 1964, 17, 1486.

[16] Greenlee R.M., Chervenak F.A., Tovell H.M.: “Incisional recurrence of a cervical carcinoma. Report of a case”. JAMA, 1981, 246, 69.

[17] Hopkins M.P., Morley G.W.: “The prognosis and management of cervical cancer associated with pregnancy”. Obstet. Gynecol., 1992, 80, 9.

[18] Sood A.K., Sorosky J.I.: “Cervical cancer diagnosed shortly after pregnancy: prognostic variable and delivery routes”. Obstet. Gynecol., 2000, 95, 832.

[19] Dupree M.T., Kitely R.A., Weismantle K., Panos R., Johnstone P.A.S.: “Radiation therapy for treatment of Bowen’s disease: lessons for lesions of the lower extremity”. J. Am. Acad. Dermatol., 2001, 45, 401.

[20] Hacker N.F., Berek J.S., Lagasse L.D., Charles E.H.: “Carcinoma of the cervix associated with pregnancy”. Obstet. Gynecol., 1982, 28, 230.

[21] Mikuta J.J.: “Invasive carcinoma of the cervix in pregnancy”. South Med. J., 1967, 60, 823.

[22] Ra K.: “Factors affecting the prognosis of cancer of the cervix in pregnancy”. Am. J. Obstet. Gynecol., 1961, 82, 45.

[23] Pradhan S., Asthana A.K., Sharan G.K.: “Recurrence of carcinoma cervix in the scar of previous cesarean section: a case report”. Int. J. Gynecol. Cancer, 2006, 16, 900.

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