Article Data

  • Views 1307
  • Dowloads 136

Original Research

Open Access

Rare case of an ovarian monodermal teratoma with functional stroma and extensive ovarian decidualization in a 74-year-old woman

  • E. Vouza1
  • Ch. Dastamani1
  • Ch. Iavazzo2
  • K. Bakalianou2
  • D. Hasiakos2
  • A. Kondi-Pafiti1,*,

1Pathology Laboratory, University of Athens, Aretaieion Hospital, Athens, Greece

22nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece

DOI: 10.12892/ejgo201102243 Vol.32,Issue 2,March 2011 pp.243-245

Published: 10 March 2011

*Corresponding Author(s): A. Kondi-Pafiti E-mail: akondi@med.uoa.gr

Abstract

We present the clinicopathological findings of a rare case of a monodermal teratoma of the right ovary with functional ovarian stroma and extensive decidualization in a 74-year-old woman. The patient presented with vaginal bleeding. Ultrasound scan revealed a pelvic mass measuring 9.5 cm in the lower right abdomen. A right oophorectomy was performed. The tumor was cystic and multilocular filled with colloid material. Histological examination revealed follicles of thyroid type, and stromal clusters of fusiform or polygonal cells were found in the stroma. An extensive decidual reaction was observed. Morphological and immunohistochemical examination of the tumor revealed cystic struma ovarii with functional ovarian stroma and ectopic decidua. Total abdominal hysterectomy with oophorectomy was performed. A benign endometrial polyp, proliferative endometrium, two fibroids, and an ovarian cyst were observed.

Keywords

Struma ovarii; Ovarian stroma; Decidua; Ovary

Cite and Share

E. Vouza,Ch. Dastamani,Ch. Iavazzo,K. Bakalianou,D. Hasiakos,A. Kondi-Pafiti. Rare case of an ovarian monodermal teratoma with functional stroma and extensive ovarian decidualization in a 74-year-old woman. European Journal of Gynaecological Oncology. 2011. 32(2);243-245.

References

[1] Szyfelbein W.M., Young R.H., Scully R.E.: “Cystic struma ovarii: A frequently unrecognized tumor. A report of 20 cases”. Am.J. Surg. Pathol., 1994, 18, 785.

[2] Iavazzo C., Vorgias G., Psarrou A., Lekka I., Katsoulis M.: “Late struma ovarii diagnosis many years after total thyroidectomy.A rare entity”. J. Buon., 2008, 13, 573.

[3] Rutgers J.L., Scully R.E.: “Functioning ovarian tumors with peripheral steroid cell proliferation: A report of 24 cases”. Int. J. Gynecol. Pathol., 1986, 5, 319.

[4] Guida M., Mandato V.D., Di Spiezio Sardo A., Di Carlo C., Giordano E., Nappi C.: “Coexistence of Graves’ disease and benign struma ovarii in a patient with marked ascites and elevated CA-125 levels”. J. Endocrinol. Invest., 2005, 28, 827.

[5] Bokhari A., Rosenfeld G.S., Cracchiolo B., Heller D.S.: “Cystic struma ovarii presenting with ascites and an elevated CA-125 level. A case report”. J. Reprod. Med., 2003, 48, 52.

[6] McCluggage W.G., Young R.H.: “Immunohistochemistry as a diagnostic aid in the evaluation of ovarian tumors”. Semin. Diagn. Pathol., 2005, 22, 3.

[7] Clement P.B., Young R.H.: “Tumor-like lesions of the ovary”. In: Clement P.B., Young R.H (eds.). Atlas of Gynecologic Oncology, 2nd edition, Philadelphia, W.B.Saunders, 2008, 294.

[8] Zhang X., Axiotis C.: “Thyroid-type carcinoma of struma ovarii”. Arch. Pathol. Lab. Med., 2010, 134, 786.

[9] Szyfelbein W.M., Young R.H., Scully R.E.: “Struma ovarii simulating ovarian tumors of other types. A report of 30 cases”. Am. J. Surg. Pathol., 1995, 19, 21.

[10] Tokunada H., Akahira J., Suzuki T.: “Ovarian epithelial carcinoma with estrogen-producing stroma”. Pathol. Internat., 2007, 57, 285.

[11] Hayasaka T., Nakahara K., Kojimahara T.: “Endometrioid adenocarcinoma with a functioning stroma”. Obstet. Gynecol. Res.,2007, 33, 381.

[12] Mils S., Carter D., Greenson J., Reuter V.E., Stoler M.H.: “Sternberg’s Diagnostic Surgical Pathology”. 5th edition, Lippincott, Williams & Wilkens, Philadelphia, 2010, 2333.

Submission Turnaround Time

Top