Outcomes of conservative surgery in early epithelial ovarian carcinoma

Objective: To investigate clinical outcomes and fertility status of conservative treatment for epithelial ovarian carcinoma. Methods: The data of clinicopathological characteristics and follow-up were retrospectively collected and analyzed in 17 patients with early epithelial ovarian carcinoma who underwent conservative surgery. Results: The tumor histologic types of 17 patients included 13 mucinous, one serous, one endometrioid, and two mixed mucinous and serous carcinomas. The FIGO stages were: ten Stage IA, six IC, and one IIIA disease. Tumor grades involved 15 grade 1 and two grade 2. Sixteen patients received adjuvant platinum-based combined chemotherapy. The medium duration of follow-up was 61 months (range 17 similar to 115 months). Only one patient recurred at 36 months after primary surgery. All of the 17 patients were alive at end of follow-up. Eight patients attempted pregnancy and five patients conceived naturally; there were six term pregnancies and one abortion. Conclusion: Conservative surgery can be considered for young patients with FIGO Stage I including grade 1 and grade 2 epithelial ovarian cancers who desire further childbearing.

Epithelial ovarian carcinoma; Conservative surgery; Recurrence; Pregnancy

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