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Radical abdominal trachelectomy is a safe and fertility preserving option for women with early stage cervical cancer
1Department of Gynecologic Oncology, Zeynep Kamil Women and Children Diseases Education and Research Hospital, Istanbul, Turkey
*Corresponding Author(s): C. KABACA E-mail: canankabaca@yahoo.com
Purpose of investigation: To present the surgical, oncological and obstetrical outcomes gained from patients who underwent radical abdominal trachelectomy (RAT) in Zeynep Kamil Women and Children Diseases Education and Research Hospital and radical Yeditepe University Hospital. Methods: A total of eight RATs were performed between 2003-2010. Data were obtained from medical and pathological records of the patients. Results: The mean age of the patients was 27.37 +/- 6.39 years. The mean follow-up time of the patients was 33.62 +/- 27.47 months. Three (37.5%) patients had a tumor size smaller than 2 cm, and five (62.5%) patients had a tumor size larger than 2 cm. Seven (87.5%) patients had Stage IB1 and one (12.5%) patient had Stage HA tumor. Three (37.5%) patients had late postoperative complications: uterotubal abscess, severe lymphedema and lymphocyst. There were no recurrences. Three patients became pregnant which resulted in two live births and one abortus. The spontaneous pregnancy rate was 50%. Conclusion: We think that RAT is a reliable surgical option for a patient with early stage cervical cancer who wants to preserve fertility.
Radical abdominal trachelectomy; Early stage cervical cancer; Pregnancy; Fertility
A. Karateke,C. KABACA. Radical abdominal trachelectomy is a safe and fertility preserving option for women with early stage cervical cancer. European Journal of Gynaecological Oncology. 2012. 33(2);200-203.
[1] International Agency for Research on Cancer. Available at: wwwdep. iarc.fr/globocan/database.htm.
[2] Seli E., Tangir J.: “Fertility preservation options for female patients with malignancies”. Curr. Opin. Obstet. Gynecol., 2005, 17, 299.
[3] Plante M.: “Fertility preservation in the management of gynecologic cancers”. Curr. Opin. Oncol., 2000, 12, 497.
[4] D’argent D., Brun J.L., Roy M., Mathevet P., Remy I.: “La trachelectomie elargie (TE), une alternative a l’hysterectomie radical dans le traitment des cancers infiltrans developpes sur la face externe du col uterin”. J. Obstet. Gynecol., 1994, 2, 285.
[5] Burnett A.F., Roman L.D., O’Meara A.T., Morrow C.P.: “Radical vaginal trachelectomy and pelvic lymphadenectomy for preservation of fertility in early cervical carcinoma”. Gynecol. Oncol., 2003, 88, 419.
[6] Plante M., Renaud M.C., François H., Roy M.: “Vaginal radical trachelectomy: an oncologically safe fertility-preserving surgery. An updated series of 72 cases and review of the literature”. Gynecol. Oncol., 2004, 94, 614.
[7] Smith J.R., Boyle D.C., Corless D.J., Ungar L., Lawson A.D., Del Priore G. et al.: “Abdominal radical trachelectomy: a new surgical technique for the conservative management of cervical carcinoma”. Br. J. Obstet. Gynaecol., 1997, 104, 1196.
[8] Ungar L., Palfalvi L,. Hogg R., Siklos P., Boyle D.C., Del Priore G. et al.: “Abdominal radical trachelectomy: fertility-preserving option for women with early cervical cancer”. BJOG, 2005, 112, 366.
[9] Abu-Rustum N.R., Sonoda Y., Black D., Levine D.A., Chi D.S., Barakat R.R.: “Fertility-sparing radical abdominal trachelectomy for cervical carcinoma: technique and review of the literature”. Gynecol. Oncol., 2006, 103, 807.
[10] Pareja F.R., Ramirez P.T., Borrero F.M., Angel C.G.: “Abdominal radical trachelectomy for invasive cervical cancer: A case series and literature review”. Gynecol. Oncol., 2008, 111, 555.
[11] Li J,. Li Z., Wang H., Zang R., Zhou Y., Ju X., Ke G. et al.: “Radical abdominal trachelectomy for cervical malignancies: Surgical, oncological and fertility outcomes in 62 patients”. Gynecol. Oncol., 2011, 121, 565.
[12] Abu-Rustum N.R., Neubauer N., Sonoda Y., Park K.J., Gemignani M., Alektiar K.M. et al.: “Surgical and pathologic outcomes of fertility-sparing radical abdominal trachelectomy for FIGO stage IB1 cervical cancer”. Gynecol. Oncol., 2008, 111, 261.
[13] Gien L.T., Covens A.: “Fertility-sparing options for early stage cervical cancer”. Gynecol. Oncol., 2010, 117, 350.
[14] Diaz J.P., Sonoda Y., Leitao M.M., Zivanovic O., Brown C.L., Chi D.S. et al.: “Oncologic outcome of fertility-sparing radical trachelectomy versus radical hysterectomy for stage 1B1 cervical carcinoma”. Gynecol. Oncol., 2008, 111, 255.
[15] Cibula D., Slama J., Fischerova D.: “Update on abdominal radical trachelectomy”. Gynecol. Oncol., 2008, 111, 111.
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